Abstract: The purpose of this study was to investigate the value of bone mineral density and necrosis volume ratio in the evaluation of postoperative curative effect of patients with femoral head necrosis. A total of 108 patients with femoral head necrosis were selected as the research object. According to follow-up, the patients were divided into disease progression group (n=44) and non-progression group (n=64). Bone density was measured by dual-energy X-ray and necrosis volume was measured by MRI. The clinical data of the two groups were compared. In the progressive group, the age, volume ratio of necrosis and the location of necrosis area in the weight-bearing area were significantly higher than those in the non progressive group (P<0.05), while the increased value of bone mineral density in the necrosis area was significantly lower than that in the non progressive group (P<0.05). Logistic regression analysis showed that the influencing factors of the disease progression of femoral head necrosis were the necrosis volume ratio, the location of the necrosis area in the weight-bearing area and the increased bone mineral density in the necrosis area (P<0.05). The area under the ROC curve of the necrosis volume ratio and the increased bone mineral density in the necrosis area for predicting disease progression were 0.808 and 0.849, respectively (P<0.05). The volume ratio of necrosis, the location of necrosis area and the increased value of bone mineral density in the necrosis area affect the postoperative curative effect of patients with femoral head necrosis, have certain application value in predicting curative effect.

Key words: bone density in necrotic area, necrosis volume ratio, femoral head necrosis, postoperative efficacy evaluation