Table of Content

15 March 2022, Volume 40 Issue 2

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2022, 40(2):  0-0. 

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Review and Articles

Application of Low Oxygen Inhibition Thiol-acrylate System in Upconversion Particles Assisted Near-Infrared Photopolymerization

PAN Yue, YANG Tianqing, HU Peng, SANG Xinxin, LIU Ren

2022, 40(2):  203-210.  DOI: 10.7517/issn.1674-0475.210901

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The presence of oxygen inhibition effect in radical photopolymerization leads to incomplete curing in the surfaces and affects the final performance of cured material. In this work, the insensitivity of thiol-acrylate system to oxygen was introduced into the upconversion particles assisted near-infrared photopolymerization (UCAP) to overcome the oxygen inhibition effect of acrylate system. The effects of the UCPs concentration, the structure and content of thiol monomers on the oxygen inhibition degree were systematically studied by combining thiols with (meth)acrylate monomers. The ATR-FTIR were used to characterize the polymerization kinetics of monocomponent (meth)acrylate and thiol-acrylate systems in UCAP. The double bond conversion at different depths of the cured material was characterized by Confocal Raman Microscopy. The results show that in the mixed system of secondary mercaptan PE-1 and acrylate monomer EM2261 with 2.0wt% UCPs and 50% -SH molarity, the maximum double bond conversion of 82% was obtained on the surface and over 90% in the deep layer, the oxygen inhibition degree of the surface layer were effectively reduced.

Synthesis and Lithographic Performance of Molecular Glass Photoresists with Covalently Bonded Photo-acid Generator

ZHANG Weijie, CHEN Jinping, YU Tianjun, ZENG Yi, LI Yi

2022, 40(2):  211-219.  DOI: 10.7517/issn.1674-0475.211001

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A molecular glass material HPS-MSF covalently bonded with photoacid generator (PAG) was designed and synthesized. It exhibits good thermal stability and film-forming properties. A negative-tone molecular glass photoresist based on HPS-MSF as the main material and 1,3,4,6-tetrakis(methoxymethyl)glycoluril (TMMGU) as the cross-linking agent was prepared. The formulation, post-baking and development conditions of the photoresist were initially studied by 254 nm ultraviolet exposure. The negative-tone photoresist was further evaluated using electron beam lithography. Patterns of a line width of 150 nm in period of 300 nm were obtained at exposure doses of 140 μC/cm² and 110 μC/cm² for photoresist containing 15% and 30% TMMGU, respectively.

Application Status and Progress of Ultrasound in Diagnosis and Treatment of Placenta Accreta Spectrum Disorders

ZHANG Jieying, WAN Hui, CHEN Haijuan, DU Jianwen, LU Yue, WANG Hong

2022, 40(2):  220-224.  DOI: 10.7517/issn.1674-0475.211126

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Placenta accreta spectrum disorders (PAS) refers to a group of diseases in which the placental tissue invades the myometrium to varying degrees. In recent years, with the liberalization of our country’s fertility policy, the increase in the rate of elderly parturients women and cesarean section, the incidence of placenta accreta has increased year by year, and the advancement of imaging technology has continuously increased the diagnosis rate of placental accreta. Conventional ultrasound, as the first choice for prenatal diagnosis of placenta accreta, has certain limitations. The new ultrasound technology can take advantage of its own and combine with conventional ultrasound to improve the accuracy of PAS diagnosis, which is conducive to the choice of clinical treatment plans and improve patients prognosis. High intensity focused ultrasound (HIFU) utilizes the thermal effect of ultrasound, uses its advantages such as non-invasive, real-time, high-efficiency, less patient pain, and quick recovery after treatment for the treatment of postpartum placenta aacreta, and has shown great application potential. This article reviews the research progress of the new technology of ultrasonography in the diagnosis and treatment of PAS.

MRI Image Enhancement Method by Gradient Field Transform

WU Mengfei, XUE Xucheng, LAN Taiji, XU Xinwei

2022, 40(2):  225-231.  DOI: 10.7517/issn.1674-0475.211002

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An improved gamma correction image enhancement method is proposed to solve the shortcomings of unclear outline, fuzzy details and excessive noise of some MRI. Firstly, the image is transformed into gradient domain to obtain the gradient field of the image. Then, the image is divided into two different gradient intervals according to the threshold, and the corresponding gamma transform is carried out in different gradient ranges to establish the target gradient field. Finally, the enhanced image is reconstructed according to the transformed target gradient field. In the process of image reconstruction, the enhanced image is obtained by numerically solving the Poisson equation. In order to solve the problem of large amount of computation of traditional algorithms, this paper first divides the image into blocks, and then combines and stitches it. The results show that this algorithm can greatly improve the information entropy and image average difference of the original image. Taking a 512×512 MRI selected in this paper as an example, this algorithm improves the information entropy of the original image from 5.50 to 6.94, and the image average difference from 33.70 to 67.44. Experimental results show that this method can effectively improve the detail and contour information of MRI without improving the image noise.

The Application Value of Ultrasound Sciatic Nerve Block in the Operation of Intertrochanteric Fractures of the Femur in the Elderly

LING Xiangwei, ZHU Jinping, LI Jiangyue, ZHANG Jingfen

2022, 40(2):  232-236.  DOI: 10.7517/issn.1674-0475.210819

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This article discussed the difference in the application effect of different approaches of ultrasound-guided sciatic nerve block in the operation of elderly femoral intertrochanteric fractures. Eighty elderly patients with femoral trochanteric fractures treated by orthopedic surgery were selected for clinical research, which were divided into group A and group B, with 40 patients in each group. Both groups were treated with general anesthesia + ultrasound-guided sciatic nerve block anesthesia. The group A nerve block approach adopted the upper lateral popliteal approach, and the B group adopted the lower lateral approach of the greater trochanter. The results showed that the operation completion time, number of punctures, needle depth, in group A were lower than those in group B (P<0.05), and the duration of nerve block in group A was longer than that in group B (P<0.05); The VAS score of group A was lower than that of group B at rest 24 h after surgery (P<0.05), and the VAS score of group A was lower than group B at 12 h and 24 h after coughing (P<0.05). It can be seen that in general anesthesia + ultrasound-guided sciatic nerve block anesthesia, the upper and lateral popliteal approach is used. The larger subtrochanterial lateral approach has advantages including shallower needle penetration, fewer punctures, shorter operation time, and lighter postoperative pain.

The Value of ¹⁸F-FDG PET/CT Technology in Evaluating the Effect of T2DM on the Efficacy of PD-L1 Targeted Therapy in Patients with Advanced Colorectal Cancer

ZHANG Xiaojie, LI Na, YANG Fang, HOU Qianqian, LI Lingling, CAI Hongxu

2022, 40(2):  237-242.  DOI: 10.7517/issn.1674-0475.210831

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This study explored the evaluation of ¹⁸F-fluorodeoxyglucose positron emission computed tomography/computed tomography (¹⁸F-FDG PET/CT) technology for the evaluation of type 2 diabetes (T2DM) on the programmed death receptor-1 ligand in patients with advanced colorectal cancer (PD-L1) The effect of treatment efficacy. A total of 104 patients with advanced colorectal cancer were selected, and they were divided into T2DM group (n=49) and no T2DM group (n=55) according to whether they were accompanied by T2DM. The efficacy and ¹⁸F-FDG PET/CT technical parameters:average standard uptake value (SUV_mean), maximum standard uptake value (SUV_max), metabolic volume (MTV), total glycolysis of lesions (TLG) were 237 compared between the two groups, and the application value of ¹⁸F-FDG PET/CT were explored. The results showed that the pathological staging, curative effect, SUV_mean, SUV_max, MTV, TLG of the T2DM group were compared with those without T2DM, and the difference was statistically significant (P<0.05); T2DM and T2DM without remission were SUV_mean, SUV_max, MTV, TLG SUVmean, SUV_max, MTV, and TLG in the T2DM group were higher than those in the non-T2DM group (P<0.05). SUV_mean, SUV_max, MTV, and TLG were negatively correlated with the efficacy (P<0.05). SUV_mean, SUV_max, MTV combined with TLG predict the highest value of T2DM unrelief. The combined detection of SUV_mean, SUV_max, MTV, and TLG with ¹⁸F-FDG PET/CT technology can evaluate the effect of T2DM on the efficacy of PD-L1 targeted therapy in patients with advanced colorectal cancer, and can objectively and quantitatively predict the patient’s response to treatment.

Efficacy and Significance of Predicting Fetal Intrauterine Growth Restriction Based on Ultrasound Detection of S/D, IFI and CPR

BAI Yanhong, RAO Hongjie, LI Min

2022, 40(2):  243-247.  DOI: 10.7517/issn.1674-0475.210902

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In this paper, the ultrasound detection of cord blood flow during systolic maximum blood flow peak/diastolic minimum blood flow peak (S/D), fetal aortic isthmus blood flow index (IFI), brain placental rate (CPR) to predict fetal intrauterine growth restriction (IUGR) efficacy and significance were studied. A total of 498 pregnant women who underwent prenatal check-ups were selected as the research objects. According to whether IUGR occurred, they were divided into IUGR group (n=33) and no IUGR group (n=465). The baseline data of the two groups were compared. S/D, IFI, CPR, estimation fetal weight (EFW), and statistical analysis of the data. The results showed that the S/D (2.90±0.52) of the IUGR group was higher than that of the no IUGR group (P<0.05), and the IFI (0.75±0.44), CPR (1.18±0.38), and EFW [(2169.33±483.05)g] were lower than those without IUGR (P<0.05) in the IUGR group; S/D was negatively correlated with EFW, and IFI, CPR and EFW were positively correlated (P<0.05). After the control of hypertension and EFW during pregnancy, S/D, IFI and CPR were still related to the occurrence of IUGR (P<0.05). Therefore, the combined detection of S/D, IFI, CPR, and EFW by ultrasound can be used as an effective program to evaluate IUGR, and provide a reference for clinical diagnosis and treatment.

Study of CDFI Parameters and Ultrasound Scores in the Diagnosis of Intrauterine Adhesions

ZENG Xiaofen, LI Na, PENG Weiling

2022, 40(2):  248-252.  DOI: 10.7517/issn.1674-0475.210903

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This study explored the value of color Doppler flow imaging (CDFI) and ultrasound scoring in the diagnosis of intrauterine adhesions. A total of 120 patients with intrauterine adhesions confirmed by hysteroscopy were selected as the adhesion group, and 120 women without intrauterine adhesions were selected as the control group. Both groups received two-dimensional ultrasound and CDFI. The measured values of uterine artery pulsation index (PI), resistance index (RI), vascular index (VI), and blood flow index (FI) in the adhesion group were lower than those in the control group (P<0.05). The ultrasound score of the adhesion group was higher than that of the control group, and the difference was significant (P<0.05). The measured values of PI, RI, VI, and FI of the severe adhesion group were lower than those of the mild and moderate groups (P<0.05). The ultrasound score of the severe adhesion group was higher than the mild and moderate groups (P<0.05). The PI, VI, and FI values of the moderate adhesion group were lower than those of the mild group (P<0.05). The ultrasound score of the moderate adhesion group was higher than that of the mild group (P<0.05). The AUC values of PI, RI, VI, FI, and ultrasound scores for the diagnosis of intrauterine adhesions were 0.684, 0.634, 0.814, 0.671, 0.905, respectively. The AUC of the five combined diagnoses was 0.939. CDFI and ultrasound scores have the advantages of convenience and non-invasiveness in clinical diagnosis of 248 intrauterine adhesions, especially the use of ultrasound scores for diagnosis has high value.

The Value of CT Plain Scan in Judging the Occurrence of Stone Incarceration in Patients with Ureteral Calculi

QIAN Nasa, QIU Lijun, MA Xin, SUI Huanhuan

2022, 40(2):  253-257.  DOI: 10.7517/issn.1674-0475.210913

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This study explored the clinical value of preoperative CT examination parameters to predict ureteral chimerism in patients with ureteral stones. Sixty-eight patients with ureteral incarcerated stones were selected as the incarcerated group, and ninety-eight patients without ureteral incarcerated were selected as the control group. Both groups received CT scan befor operation. The sensitivity, specificity and AUC of stone length in the diagnosis of ureteral calculi incarceration were 83.15%, 70.69% and 0.836, respectively. The sensitivity, specificity and AUC of ureteral calculi incarceration were 78.85%, 61.33% and 0.745, respectively. The results of logistic regression model showed that the risk of ureteral calculi incarceration in patients with ipsilateral calculi surgery history, increased ureteral wall thickness, longer calculi length and larger calculi volume was higher (P<0.05). The load parameters of CT examination of stones have a certain value for the diagnosis of patients with stone incarceration. The increase in the length and diameter of stones and the thickening of the ureteral wall will increase the risk of stone incarceration in patients.

The Relationship between the Quantitative Parameters of Susceptibility Imaging and the Severity and Prognosis of Parkinson’s Disease

DENG Kuipin, LIU Tiejun, ZHENG Yingjie, HUANG Dong, HUANG Guangsu

2022, 40(2):  258-262.  DOI: 10.7517/issn.1674-0475.210907

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In order to explore the relationship between the substantia nigra, red nucleus susceptibility value of quantitative susceptibility imaging and the degree of Parkinson’s disease (PD) and the value of predicting the short-term prognosis, fifty-four patients with PD were selected as the research object, and they were divided into a good prognosis group based on the recent prognosis (39 cases) and poor prognosis group (15 cases). The results showed that the substantia nigra and red nucleus susceptibility values of the poor prognosis group were higher than those of the good prognosis group (P<0.05); the substantia nigra and red nucleus susceptibility values of patients with stage Ⅳ-Ⅴ were higher than those of stage Ⅲ, Ⅰ-Ⅱ, and stage Ⅲ patients higher than that in patients with stage Ⅰ to Ⅱ (P<0.05); there is a positive correlation between the substantia nigra and red nucleus susceptibility values and the severity of the disease (P<0.05); the substantia nigra and red nucleus susceptibility values are still significantly related to the short-term prognosis of PD patients (P<0.05). The area under the curve (AUC) of substantia nigra and red nucleus susceptibility predicting poor prognosis of PD were 0.708 and 0.678, respectively, and the combined predicted AUC was the largest, which was 0.846. Based on this, it can be seen that the magnetic susceptibility values of the substantia nigra and red nuclei are positively correlated with the severity of PD. Quantitative magnetic susceptibility imaging measurement has high application value in predicting the short-term prognosis of PD.258

Correlation of DCE-MRI Parameters and Expression of miR-27 and miR-155 with Breast Cancer

QIN Kai, YE Fei, GU Guiyuan, BEN Teng, LU Songhua

2022, 40(2):  263-268.  DOI: 10.7517/issn.1674-0475.210917

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The purpose of this study was to explore the relationship between dynamic enhancement of magnetic resonance, miR-27, miR-155 expression and breast cancer. One hundred breast cancer patients were selected as the observation group, and another 60 patients with benign breast lesions were selected as the control group. This study compared the two groups’ DCE-MRI quantitative parameters [transport constant (K_trans), rate constant (K_ep), extravascular intercellular space fraction (V_e)] and the expression of miR-27 and miR-155, and then performed correlation analysis to evaluate its diagnostic power. The expression levels of K_trans, K_ep, miR-27 and miR-155 in the observation group were higher than those in the control group (P<0.05). The expression levels of K_trans and K_ep in breast cancer patients were significantly positively correlated with the expression levels of miR-27 and miR-155 (P<0.05). K_trans, K_ep, miR-27 and miR-155 were independent influencing factors of breast cancer (P<0.05). The expression of K_trans, K_ep, miR-27, miR-155 is related to histological grade, clinical stage, lymph node metastasis, progesterone and estrogen receptor expression (P<0.05). The AUC of the combined diagnosis of breast cancer by DCE-MRI quantitative parameters, miR-27, miR-155 expression is 0.905. DCE-MRI quantitative parameters (K_trans, K_ep) and the expression levels of miR-27 and miR-155 were up-regulated in breast cancer, and were related to pathological features.

Analysis of the Value of 3D-PDU Combined with Serum to Detect Central Placenta Previa and Placenta Accreta

SHEN Jie, REN Qing, LIAO Weiwei, ZHENG Weixiu, DENG Senling, LIN Yuan

2022, 40(2):  269-274.  DOI: 10.7517/issn.1674-0475.210918

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This study investigated the value of three-dimensional power Doppler ultrasound (3D-PDU) combined with serum in detecting central placenta previa and placenta implantation. Fifty-two patients with central placenta previa (CPP) and placenta accreta (PA) were selected as the PA group, and 52 patients with CPP without PA during the same period were selectedas the PA group. Ultrasound examination of 52 normal pregnant women with placenta attached to the anterior uterine wall was the control group. All were examined by 3D-PDU, and the levels of blood alpha-fetoprotein (AFP) and soluble vascular endothelial growth factor receptor 1 (SFlt-1) were detected. After analysis, it was found that the levels of VI, FI, VFI, and serum AFP in the PA group were higher than those in the PA-free group and the control group, and the SFlt-1 levels were lower than those in the PA-free group and the control group (P<0.05). The AUC of VI, FI, VFI, AFP and SFlt-1 combined to diagnose CPP and PA was greater than the AUC diagnosed by each index alone, and the sensitivity and specificity of the combined diagnosis are 90.59% and 76.47%, respectively. The incidence of PA in patients with high expression of VI, FI, VFI, and serum AFP is higher than that of 269those with low expression, and SFlt-1 is low The incidence of PA in expressers was higher than that in high expressers (P<0.05). The use of 3D-PDU combined with blood AFP and SFlt-1 level diagnosis is expected to provide an effective way for clinical diagnosis and treatment of CPP and PA.

Ultrasound Evaluation of Blood Vessel Diameter and Blood Flow before and after the Maturation of Forearm Arteriovenous Fistula

XIE Jing, WANG Chunjie

2022, 40(2):  275-279.  DOI: 10.7517/issn.1674-0475.210924

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This article explored the changes and significance of the blood vessel diameter and blood flow before and after the maturation of the autogenous arteriovenous fistulas (AVF) in the forearm of dialysis patients. A total of 109 end-stage renal disease dialysis patients receiving forearm AVF angioplasty were selected as the research objects. According to whether the fistula was mature within 8 weeks after operation, they were divided into mature group (n=68) and immature group (n=41). The clinical data of the two groups were compared. The internal diameter and blood flow of the cephalic vein and radial artery before and 8 weeks after the operation, and the data were analyzed and processed. The results showed that the internal diameter and blood flow of the cephalic vein and radial artery in the two groups were higher than that before the operation at 8 weeks after operation, and the mature group was higher than that of the immature group (P<0.05); multivariate logistic regression analysis showed that the cephalic vein and radial Arterial vessel diameter and blood flow are still related to fistula maturity (P<0.05). The area under the curve (AUC) of the combined assessment of cephalic vein and radial vein vessel diameter and blood flow for fistula maturity is greater than the individual parameters. The evaluation value is the highest; the maturity rate of patients with high level of cephalic 275 vein and radial artery diameter and blood flow is higher than that of low level (P<0.05). It can be seen that the internal diameter and blood flow of the cephalic vein and radial artery after the mature AVF of the forearm are significantly increased. The use of ultrasound to detect the changes of blood vessels before and after AVF angioplasty can be used as a standard for evaluating the maturity of internal fistulas and provide a reference for clinical selection of puncture dialysis timing.

Study on Diagnosis of Fetal Intrauterine Hypoxia in Pregnant Women with Hypertension During Pregnancy Based on 3D-CPA

XU Yan, YU Haijing, XIA Honglin, HUANG Yan

2022, 40(2):  280-285.  DOI: 10.7517/issn.1674-0475.210925

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This article explored the relationship between intrauterine hypoxia in pregnant women with pregnancy-induced hypertension and the changes in brain and placental parameters detected by three-dimensional power Doppler (3D-CPA). One hundred confirmed pregnant women with hypertension during pregnancy were selected as the case group, and 100 pregnant women with normal pregnancy in the same period were selected as the control group. 3D-CPA was used to examine the fetal brain and placental blood perfusion parameters of the two groups, and the two groups of fetal delivery were detected after the level of oxidative stress products in cord blood, the correlation between 3D-CPA parameters and oxidative stress products was analyzed. The blood vessel index (VI), blood flow index (FI), and vascular blood flow index (VFI) measured values in the placenta tissue of the case group were lower than those of the control group (P<0.05). VI, FI, VFI measured value in the fetal brain of the case 280 group was greater than that of the control group (P<0.05). The measured values of VI, FI, and VFI in the placental tissue of the preeclampsia group were lower than those of the hypertensive disorder group during pregnancy (P<0.05). The measured values of FI, VFI and VI in the fetal brain of the preeclampsia group were greater than those of the hypertensive disease group during pregnancy (P<0.05). The cord blood of the case group contained malondialdehyde (MDA), 8-isoprostaglandin (8-iso), Oxidized low-density lipoprotein (ox-LDL) and heat shock protein-70 (HSP-70) were significantly higher than those of the control group (P<0.05). The VI and VFI in the placenta tissue of patients with pregnancy-induced hypertension were significantly negatively correlated with the levels of MDA, ox-LDL, 8-iso, and HSP-70 in the patient’s cord blood (P<0.05), and FI was significantly negatively correlated with ox-LDL, 8-ISO and HSP-70 (P<0.05). The VI of the fetal brain in the pregnancy-induced hypertension group was significantly positively correlated with MDA, 8-iso, and HSP-70 in the umbilical cord blood of the patients (P<0.05), and VFI was significantly positively correlated with 8-iso and HSP-70. 3D-CPA examination can find that the level of fetal placental blood flow parameters of pregnant women with pregnancy-induced hypertension is reduced, and the craniocerebral blood flow parameters are compensatedly increased, and it is related to intrauterine hypoxia.

Magnetic Resonance Imaging Study of Brain Function and Structure Changes in Patients with Post-herpetic Neuralgia

BAI Lala, YANG Wei, ZHOU Miao, HUANG Guobiao

2022, 40(2):  286-290.  DOI: 10.7517/issn.1674-0475.211101

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This study explored the clinical value of magnetic resonance imaging (MRI) in patients with post-herpetic neuralgia (PHN) in assessing brain functional divisions and gray matter volume changes. Thirty-four patients with PHN (PHN group) and 40 healthy volunteers (control group) were selected as the research subjects. They received resting state functional magnetic resonance imaging (rs-FMRI), and the differences in low-frequency amplitude values between the PHN group and the control group were compared. The results showed that the low-frequency amplitude values of the PHN group in the brain stem, left and right temporal lobes, left and right frontal lobes, right anterior cingulate gyrus, and right parietal lobe were higher than those in the control group (P<0.05). The low-frequency amplitude values of PHN group had left and right insula, middle frontal gyrus, left and right central anterior gyrus, right hippocampus, and right fusiform gyrus were significantly lower than those of the control group (P<0.05). The amplitude increases of low-frequency in brain stem, left and right temporal lobes, left and right frontal lobes, and right cingulate gyrus and left parietal lobe of PHN patients were positively correlated with the VAS score. Low-frequency amplitude reduction values of left and right insula, middle frontal gyrus, left and right central anterior gyrus, right para 286 hippocampal gyrus, and right fusiform gyrus were negatively correlated with the VAS score. In the resting state, the brain functional areas of PHN patients changed compared with the normal population, which may be related to the increased pain perception level of the patients.

Analysis of the Diagnosis and Treatment of Complicated Congenital Heart Disease with 320-Slice CT Combined with TTE

GAO Haichao, LI Shucheng, KONG Fanqiang, LI Dongyang, WANG Qingsong, WANG Xibing, WANG Zhuxiu

2022, 40(2):  291-295.  DOI: 10.7517/issn.1674-0475.211103

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This study explored the application value of 320-slice CT angiography (CTA) combined with transthoracic echocardiography (TTE) in the diagnosis and treatment of complex congenital heart disease. A total of 66 patients with ventricular septal defect (VSD) and atrial septal defect (ASD) repaired were selected for study. All children underwent TTE and CTA examinations, and the difference in the defect diameters of VSD and ASD detected by TTE and CTA were compared. A total of 118 congenital heart diseases such as ASD and VSD were found after surgical treatment and operation. The correct detection rate of CTA in 118 congenital heart disease types was 78.81%, which was higher than 64.41% of TTE, and the difference was statistically significant (P<0.05). The correct detection rate of CTA combined with TTE in 118 congenital heart disease types was 94.07%, which was higher than 78.81% of CTA alone, and the difference was statistically significant (P<0.05). CTA combined with TTE can significantly improve the diagnostic accuracy in the diagnosis and treatment of complex congenital heart disease compared with the two alone, which is of great value for clinical diagnosis and treatment.

Preoperative T Staging of Rectal Cancer Diagnosed by MRI Texture Analysis and Its Relationship with Tumor Differentiation

ZHANG Yilan, SHI Xun, ZHANG Huili, XU Feng, DONG Congsong

2022, 40(2):  296-300.  DOI: 10.7517/issn.1674-0475.210906

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This study explored the value of MRI texture analysis in the preoperative T staging diagnosis of rectal cancer and its relationship with the degree of tumor differentiation. Seventy-two patients with rectal cancer were selected as the research objects, and MRI texture analysis was performed. The results showed that the mean value of MRI texture parameters, contrast, autocorrelation, entropy, variance, and preoperative T staging of rectal cancer were all influencing factors. The preoperative T staging AUC of each parameter in the combined diagnosis of rectal cancer was 0.951, which was significantly higher than that of a single parameter. The MRI texture parameters of patients with different tumor differentiation levels are significantly different. The mean, autocorrelation, entropy, variance and the tumor differentiation are negatively correlated, and the contrast is positively correlated with the tumor differentiation (P<0.05). The mean value of MRI texture parameters, contrast, autocorrelation, entropy, and variance are the influencing factors of preoperative T stage of rectal cancer, which can be used for the diagnosis of T stage and are related to the degree of tumor differentiation.

Study on the Relationship between Quantitative Parameters of CT Spectroscopy Technology and AFP, DCP and the Efficacy of Diagnosing Liver Cancer

DU Lin, WANG Yu

2022, 40(2):  301-305.  DOI: 10.7517/issn.1674-0475.210908

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This study investigated the relationship between the quantitative parameters of computed tomography (CT) spectroscopy technology and alpha-fetoprotein (AFP), abnormal prothrombin (des-γ-carboxyprothrombin, DCP) and the diagnostic efficiency of hepatocellular carcinoma (HCC). Sixty-one patients with HCC (HCC group) and 61 patients with benign liver lesions (benign group) were selected as the study subjects. The lesion-liver contrast noise ratio (CNR), calcium (fat) concentration, fat (calcium) concentration, water iodine concentration, lesion-to-normal hepatic tissue ratio (LNR) and normalized iodine concentration (NIC) were compared between the two groups at a single energy level of 40-140 keV in arterial phase and portal vein phase. The results showed that the arterial phase two groups had the best CNR up to 50 keV, and the portal phase HCC group had the best CNR up to 70 keV. The arterial phase and portal phase calcium (fat) concentration, LNR, and NIC of the HCC group were lower than those of the benign group. The concentration of fat (calcium) was higher than that of the benign group (P<0.05), and each index was significantly correlated with AFP and DCP (P<0.05). The AUC of the CNR of 50 keV in the arterial phase combined with the arterial NIC for the diagnosis of HCC was 0.935. Therefore, the best single-energy image can be obtained by detecting the best CNR by CT spectroscopy. The 50 keV CNR and NIC in the arterial phase are related to AFP and DCP. The combined detection can 301 be used as a non-invasive method for diagnosing HCC.

Correlation between CT Findings and Pathological Grade of Lung Adenocarcinoma

WANG Rui, MA Cailing, HU Jiuli, WANG Qiongge, HU Chanchan

2022, 40(2):  306-310.  DOI: 10.7517/issn.1674-0475.210824

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This article aims to explore the correlation between CT imaging findings and histopathological grading of lung adenocarcinoma.A retrospective collection of 149 patients with pathologically confirmed lung adenocarcinoma, according to the grading standard, the patients were divided into a moderately well-differentiated group (level Ⅰ and Ⅱ), a poorly differentiated group (level Ⅲ), and the relationship between CT imaging manifestations of lung adenocarcinoma and postoperative pathological grading was analyzed. Results: (1) The smallest and largest diameters of the tumors in the moderately well-differentiated group were significantly lower than those in the poorly differentiated group (P<0.05). (2) 47.4% of the tumor marginal signs in the moderately well-differentiated group showed lobular signs, while 68.5% in the poorly differentiated group, there was a significant difference between the two group (P<0.01). (3) 26.3% of the moderately differentiated group has ground glass shadow, and 3.7% of the poorly differentiated group, there was a significant difference between the two group (P<0.01). In short, the CT appearance of lung adenocarcinoma is significantly correlated with its pathological grade.

Application of SCTP Technical Parameters in the Diagnosis and Prognosis of Early Avascular Necrosis of the Femoral Head

ZHANG Jing, GUO Ningru, JIAN Xianan, LI Dandan, WU Yafang

2022, 40(2):  311-315.  DOI: 10.7517/issn.1674-0475.210928

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This study explored the diagnostic value of digital subtraction CT perfusion imaging (SCTP) technology in detecting blood flow (BF), blood volume (BV), and mean transit time (MTT) on early avascular necrosis of the femoral head (ANFH) and its impact on prognosis. Sixty-six patients with unilateral ANFH were taken as the research object. SCTP technique was performed on the femoral head of the affected and healthy side. The results showed that the BF and BV of the femoral head of the affected side were lower than that of the healthy side, and the MTT was longer than that of the healthy side (P<0.05). The AUC of bone BF, BV, and MTT to diagnose ANFH was 0.866, 0.755, and 0.820. The AUC of the three combined diagnosis of ANFH was 0.911, the sensitivity was 95.45%, the specificity was 83.33%, and the diagnostic value was higher than that of a single diagnosis (P<0.05). Follow-up for 1 year, 4 cases were lost to follow-up. Among the 62 patients, 41 had a good prognosis and 21 had a poor prognosis. There were statistically significant differences in disease stage, necrotic volume, necrotic location, femoral head BF, BV, and MTT in patients with different prognosis (P<0.05). Femoral head BF and BV were negatively correlated with disease stage and necrotic volume, and MTT was correlated with disease stage, the volume of necrosis was positively correlated 311 (P<0.05). Femoral head BF, BV, MTT were important prognostic factors (P<0.05). Therefore, the SCTP detection of femoral head BF, BV, and MTT has a reliable value in the early diagnosis of ANFH, and it can also provide an important reference for clinical prediction and prognosis assessment.

Value of Dynamic Electrocardiogram Combined with Clinical Pathway in Evaluating Coronary Heart Disease with Arrhythmia

LI Yanli, SUN Jing, CHEN Yan, YANG Mei

2022, 40(2):  316-319.  DOI: 10.7517/issn.1674-0475.210818

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The purpose of this study was to explore the value of 12 lead Holter combined with clinical pathway evaluation in the diagnosis of coronary heart disease with arrhythmia. All patients were given 12 lead ambulatory ECG combined with clinical pathway evaluation. The results show that, the detection rate of arrhythmia in ambulatory ECG was significantly higher than that in routine ECG (P<0.05). The areas under the ROC curve of QTc interval and QRS time limit in predicting the poor prognosis of coronary heart disease were 0.733 and 0.802, respectively (P<0.05). The area under ROC curve of poor prognosis predicted by clinical pathway evaluation system combined with 12 leads was 0.901 (P<0.05). 12 lead ambulatory electrocardiogram combined with clinical pathway evaluation system has good application value in the diagnosis of coronary heart disease with arrhythmia.

HRCT Quantitative Evaluation of the Clinical Effect of Inhaled Corticosteroids in the Treatment of Children with Asthma

MO Changyou, LI Chao, XIE Yun

2022, 40(2):  320-324.  DOI: 10.7517/issn.1674-0475.210822

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The purpose of this study was to evaluate the clinical effect of inhaled glucocorticoids on asthmatic children by high resolution CT (HRCT). 118 children with asthma were divided into observation group (n=63) and control group (n=55). The control group was given routine treatment, the observation group was given fluticasone propionate aerosol or Budesonide aerosol on the basis of the control group, the therapeutic effects of the two groups were observed, the thickness of segmental and sub segmental bronchial wall/airway outer diameter (T/D) and the percentage of airway wall area in total airway area (WA) were measured by HRCT. The therapeutic effect of the observation group was better than that of the control group (P<0.05). T/D and WA in the observation group were significantly lower than those in the control group (P<0.05). Compared with ineffective patients, effective patients had lower T/D and WA after treatment (P<0.05). The area under ROC curve of T/D and WA was 0.859 and 0.826, respectively, P<0.05. Inhaled glucocorticoids have a good effect on children with asthma, and HRCT quantitative parameters have a certain value in predicting the therapeutic effect.

CT and MRI Observation of OLIF Combined with Posterior Fixation for Lumbar Spondylolisthesis Stenosis

DU Yingjie, LI Xiaojun, WANG Yuman

2022, 40(2):  325-330.  DOI: 10.7517/issn.1674-0475.210915

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This article discussed the application value of oblique lateral interbody fusion (OLIF) combined with posterior fixation in the treatment of patients with L4/L5 lumbar spondylolisthesis and spinal stenosis based on CT and magnetic resonance imaging techniques. A retrospective study of 118 patients with L4/L5 lumbar spondylolisthesis and spinal stenosis who underwent OLIF combined with posterior fixation was selected for a retrospective study, and the patients were divided according to the 1-year follow-up effect. There were 92 cases in the excellent group and 26 cases in the non-excellent group. The results showed that the height of the intervertebral space, the area of the intervertebral foramen, and the area of the spinal canal in the excellent group were all larger than those in the non-excellent group (P<0.05). The increase in the cross-sectional area of L4 and L5 psoas major and the cross-sectional area of L4 and L5 paraspinal muscles in the excellent group were greater than those in the non-excellent group (P<0.05). The ODI reduction and VAS reduction scores of the excellent group were greater than those of the non-excellent group (P<0.05). The increase of intervertebral space height, intervertebral foramen area, spinal canal area, L4 and L5 paravertebral 325 muscle cross-sectional area were significantly positively correlated with the difference in ODI before and after surgery (P<0.05). CT and MRI are used to follow up patients with L4/L5 lumbar spondylolisthesis and spinal stenosis after OLIF combined with posterior fixation, it can observe the situation of postoperative foraminal stenosis and the recovery of psoas major and paraspinal muscles after clinical symptoms are relieved. The recovery situation is of certain value for judging the patient's lumbar function recovery and surgical effect.

Characteristics and Significance of Electrocardiographic P Wave in Patients with Essential Hypertension Complicated with Paroxysmal Atrial Fibrillation

WU Jun, XU Libing

2022, 40(2):  331-334.  DOI: 10.7517/issn.1674-0475.210826

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This study explored the predictive value of ECG P wave characteristics in patients with essential hypertension complicated with paroxysmal atrial fibrillation. 66 essential hypertension patients with paroxysmal atrial fibrillation were selected (observation group), and 80 patients with unilateral essential hypertension were selected as the control group, ECG parameters were compared between the two groups, the P-wave maximum duration (Pmax), P-wave dispersion (Pd) and P-wave variation (Pv) in the observation group were significantly higher than those in the control group, respectively (P<0.05). The area under the ROC curve of Pmax, Pd and Pv in predicting paroxysmal atrial fibrillation was 0.709, 0.944 and 0.528. Pmax, Pd and Pv in the observation group were significantly lower than those before treatment (P<0.05). The area under the ROC curve of effective predicted by Pd was 0.878 (P<0.05), while the area under the ROC curve of effective predicted by Pmax was 0.621 (P>0.05). The P wave feature has certain application value in predicting the concurrent paroxysmal atrial fibrillation and the curative effect of sacubitril and valsartan.

Application Effects of Different Ultrasound Techniques and TI-RADS in Lymph Node Metastasis of Thyroid Cancer

LI Zhaoxi, WEN Dehui, LU Haiyong, LIU Weiliang

2022, 40(2):  335-338.  DOI: 10.7517/issn.1674-0475.210817

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This study investigated the application effects of high-frequency color Doppler ultrasound, ultrasound elastography and the thyroid imaging reporting and data system (TI-RADS) in cervical lymph node metastasis of thyroid cancer. Eighty-six patients with thyroid cancer confirmed by surgery or biopsy were retrospectively analyzed. The pathological results were taking as the standard to evaluate the diagnostic value of color Doppler ultrasound, ultrasound elastography and TI-RADS using the receiver operating characteristic (ROC) curve. It was found that the sensitivity of high-frequency color Doppler ultrasound, ultrasound elastography and TI-RADS in the diagnosis of lymph node metastasis was 75.93%, 74.07% and 70.37%, significantly lower than 90.74% of combined diagnosis of the three. Therefore, the combination of high-frequency color Doppler ultrasound, ultrasound elastography and TI-RADS is of great value in the diagnosis of cervical lymph node metastasis of thyroid cancer, which can provide valuable information for clinical diagnosis, treatment and prognosis.

Treatment of Atrial Septal Defects by Minimally Invasive Closure of Different Paths under the Guidance of Transesophageal Ultrasound Clinical Controlled Study

YANG Yujing, LEI Fang, ZHOU Hongzheng, JIANG Yaqun, WANG Wei

2022, 40(2):  339-343.  DOI: 10.7517/issn.1674-0475.210827

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The effect of minimally invasive closure of atrial septal defect through different paths under the guidance of transesophageal ultrasound were investigated. A total of 80 patients with atrial septal defect (ASD) were divided into observation group (percutaneous group) and control group (right chest group) according to the treatment method. Under the guidance of transesophageal ultrasound, percutaneous closure was used in the observation group and right thoracic closure was used in the control group. The changes of relevant indexes before and after operation were compared between the two groups. The results showed that the right atrial transverse diameter, right ventricular transverse diameter, pulmonary artery diameter and tricuspid regurgitation area in the study group were significantly lower than those in the control group (P<0.05). After operation, the incision length, operation time, ICU stay and VAS score in the observation group were lower than those in the control group, and the difference was statistically significant (P<0.05). Compared with the control group, LVSD decreased, LVEF and 6 min walking distance increased in the study group (P<0.05). Transesophageal ultrasound-guided percutaneous closure in the treatment of ASD has good curative effect, less trauma and high safety.

The Application Value of Intelligent Palm Color Doppler Ultrasound in the Treatment of Arteriovenous Fistula in Patients with End-stage Renal Disease

ZHANG Wenji, LIU Ding, ZHAO Yingying, ZHANG Wanzhe

2022, 40(2):  344-347.  DOI: 10.7517/issn.1674-0475.210914

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This study explored the application value of intelligent handheld color Doppler ultrasound in patients with end-stage renal disease. A total of 80 patients with end-stage renal disease were divided into observation group (n=45) and control group (n=35). All patients underwent intravenous fistula. The observation group was given intelligent palm color ultrasound evaluation, and the control group was given routine color ultrasound evaluation, and the differences between the two groups were analyzed. The results showed that the observation group of operation time was significantly lower than the control group (P<0.05). The surgical success rate, radial diameter and blood flow were significantly higher in 1 month after surgery than in the control group (P<0.05). The maturity time of arteriovenous fistula was significantly faster than the control group (P<0.05). Smart palm color ultrasound was useful in moving intravenous fistula in patients with end-stage renal disease. Helps to shorten the operation time, improve the surgical success rate. Accelerate the maturity of the arteriovenous fistula.

Application of Echocardiography in the Evaluation of Segmental Ventricular Wall Motion Abnormalities in Coronary Heart Disease

YI Huaihong, ZHOU Xing, CAI Feifei

2022, 40(2):  348-352.  DOI: 10.7517/issn.1674-0475.210828

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The purpose of this study was to explore the value of echocardiography in the evaluation of segmental wall motion abnormalities in coronary heart disease. 89 patients with coronary heart disease with segmental wall motion abnormality were selected. Echocardiography and percutaneous coronary intervention (PCI) were performed. The peak of myocardial systolic velocity (PMSV) and peak of myocardial diastolic velocity (PMDV) in each segment of interventricular septum, lateral wall, anterior wall, inferior wall and anterior septum after operation, and global area strain of the heart (GAS), left ventricular ejection fraction (LVEF), left ventricular end systolic volume (LVESV) and left ventricular end diastolic volume (LVEDV) were significantly improved compared with those before surgery (P<0.05). The area under the ROC curve for GAS was 0.774 (P>0.05). Echocardiography has a good application value in the clinical pathway evaluation system of coronary heart disease segmental ventricular wall motion abnormality, which is helpful for the detection of disease and the prediction of therapeutic effect.

Application of CTA Combined with CDFI in the Repair of Soft Tissue Injury with Anterior Thigh Perforator Flap

ZHANG Wei, LIU Qianyun, ZHANG Yang

2022, 40(2):  353-356.  DOI: 10.7517/issn.1674-0475.210830

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This article explored the application of CT angiography(CTA) imaging combined with color Doppler flow imaging (CDFI) in the repair of soft tissue injuries of the upper and lower extremities with external perforator flaps. Fifty-eight patients planned to undergo anterolateral thigh perforator flap (ALTPF) transplantation were selected in this hospital and divided into CTA group and CDFI group, each with 29 cases. CTA and CDFI were used for skin grafting before surgery. The flap design and the positioning of the anterior and outer perforating branches of the bone, observe the repair of the subjects. The results showed that the skin temperature of the flaps in the CTA group and the CDFI group was higher in 1 case, and the other temperatures were in the normal range. There was no risk of blood vessels and all survived; the average flow velocity and the maximum value of the descending branch of the lateral femoral circumflex artery in the CTA group and the CDFI group. There was no significant difference in flow rate (P>0.05). Both CDFI and CTA can be applied to the anterior thigh and outer perforator flap to meet the needs of reconstructing soft tissues in the upper and lower limbs.

Risk Factors for Severe Bleeding after an Ultrasound-guided Percutaneous Renal Puncture Biopsy

ZHOU Dawei, ZHENG Li, LIANG Fadong, ZHU Zhengtao, CHEN Jie

2022, 40(2):  357-361.  DOI: 10.7517/issn.1674-0475.210832

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This paper discussed the investigate the risk factors of severe bleeding after ultrasound-guided percutaneous renal biopsy. 512 patients underwent ultrasound-guided percutaneous renal biopsy were retrospectively selected, the patient’s serum indexes were detected, the occurrence of severe bleeding and its influencing factors were analyzed. In severe hemorrhage group, the ultrasound demarcated skin and medulla were not clear, serum creatinine (SCR) were significantly higher than those in control group (P<0.05), while the estimated glomerular filtration rate (eGFR), hemoglobin (Hb) and platelet (PLT) were significantly lower than those in control group (P<0.05). Logistic regression analysis showed that unclear boundary between skin and medulla, Scr, Hb and eGFR were the influencing factors of severe bleeding after ultrasound-guided percutaneous renal biopsy (P<0.05). Severe bleeding after ultrasound-guided percutaneous renal biopsy is affected by boundary between skin and medulla, Scr, Hb and eGFR.

CBCT Observation of Alveolar Bone Resorption and Stability Analysis of Immediate Implant

GUI Fang, LIU Guihong, MA He, MENG Qingwei, GOU Jingxue

2022, 40(2):  362-366.  DOI: 10.7517/issn.1674-0475.210910

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The purpose of this study was to observe alveolar bone resorption and implant stability after immediate implantation with cone beam CT (CBCT). A total of 330 implants were implanted in 200 patients who underwent implant repair in our hospital, the CBCT was used to measure the alveolus absorption of immediate implantation and the Hounsfield unit (HU) value of jaw bone in the planted area, the Qstell ISQ implant stability measurement instrument was used to measure the implant stability quotient (ISQ). Analysis of variance was used for the difference between groups, and Pearson correlation analysis was used for correlation. One year after the operation, the bone absorption of mandibular anterior teeth and mandibular posterior teeth were significantly less than that of maxillary anterior teeth and maxillary posterior teeth (P<0.05); 1 year after surgery, there was no significant difference in PES score of maxillary anterior teeth, maxillary posterior teeth, mandibular anterior teeth and mandibular posterior teeth (P>0.05). The HU values of mandibular anterior teeth and mandibular posterior teeth were (79.20±8.02) and (78.43±9.11), respectively, which were significantly higher than that of maxillary anterior teeth and maxillary posterior teeth (P<0.05). The ISQ values of the implants with diameters of 4.3 mm and 5.0 mm were significantly higher than that of the implants with diameters of 3.5 mm (P<0.05). The ISQ value of implant was positively correlated with the HU value of jaw bone (r=0.439, P=0.000< 0.05). CBCT has certain application value in the observation of alveolar bone absorption after immediate 362 implantation, and the stability of the implant is related to the planting area, the HU value of jaw bone and the implant diameter.

Study on Holter-assisted CDFI in Predicting Fetal Distress

LI Chun, SUN Yanfang, YANG Yi, WANG Huimin, ZHOU Si

2022, 40(2):  367-371.  DOI: 10.7517/issn.1674-0475.210911

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This paper discussed the value of the maternal dynamic ECG monitoring (Holter) assisted color Doppler ultrasound (CDFI) and Tei index in predicting fetal intrauterine distress. The pregnant women who registered and gave birth were selected as the research object. Among them, 53 pregnant women with fetal distress symptoms were selected as the distress group, and 100 pregnant women without fetal distress symptoms during the same period were selected as the control group. The two groups were monitored by Holter, and CDFI was used to detect fetal umbilical artery and middle cerebral artery resistance index (RI), pulsatility index (PI), systolic to diastolic peak blood flow ratio (S/D), and Tei index. The PELV values in the distress group were higher than those in the control group (P<0.05). The measured values of PI, RI, and S/D of the umbilical artery and middle 367 cerebral artery in the distress group were higher than those in the control group (P<0.05). The Tei index value of the distress group was higher than that of the control group (P<0.05). The best cut-off value of PELV value for predicting fetal distress was 18.68%, and the area under the curve was 0.655. The sensitivity of PELV + umbilical artery S/D value + brain arterial S/D value + Tei index to predict fetal distress was 90.57%, and specificity was 87.00%. Clinically, the sensitivity of Holter alone to predict fetal distress is poor. As an auxiliary method, combined with CDFI and Tei index to predict fetal distress has a better effect.

Diagnosis and Correlation Analysis of Bladder Space Occupying Lesions by Contrast-enhanced Ultrasound

LI Feng, SHAO Jichun, YANG Jianbo, SHI Bo

2022, 40(2):  372-376.  DOI: 10.7517/issn.1674-0475.210912

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This study explored the value of contrast-enhanced ultrasound (CEUS) in the differentiation of benign and malignant bladder occupying lesions. Eighty-two patients with space-occupying bladder lesions were selected as the research object, there were a total of 105 lesions. The differences of contrast-enhanced ultrasound parameters between benign and malignant lesions were compared, including time to arrival (AT), time to peak (TTP), peak intensity (PI) and washout time (WT). The results showed that 61 malignant lesions were confirmed pathologically after operation, and the sensitivity, specificity and accuracy of CEUS in diagnosing malignant bladder lesions were 90.16%, 90.91% and 90.48% respectively. PI and WT values of the high-grade malignant lesions were significantly higher than those of the low-grade malignant lesions (P<0.05). The PI and WT of T stage≥T3 lesions were significantly higher than those of Ta-1 and T2 lesions (P<0.05). The areas under the ROC curve of PI and WT for predicting high-grade lesions were 0.712 and 0.888, respectively. The areas under the ROC curve of PI and WT in predicting T stage ≥ T3 lesions were 0.812 and 0.852, respectively. CEUS is of high value in the diagnosis of bladder space occupying lesions, preoperative T staging and pathological grading, and is worthy of clinical use.

Application of MSCT in Evaluating Liver Volume and Spleen Volume in Diagnosing Liver Cirrhosis and Liver Reserve Function

SHI Wenda, CUI Zhixin, ZHANG Dan, LI Guiping, WANG Guoyu, ZHAO Xiaobin, XIAO Xu, WANG Min

2022, 40(2):  377-381.  DOI: 10.7517/issn.1674-0475.210920

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This study discussed the application value of MSCT in evaluating liver volume and spleen volume in the diagnosis of liver cirrhosis and liver reserve function. In this study, a case-control study was conducted. A total of 120 patients with liver cirrhosis (case group) and 120 volunteers with matched age, gender and no liver disease (control group) were selected. The volumes of the whole liver, liver lobe and spleen of the two groups were detected by MSCT. The total liver volume, right half liver volume, left internal lobe volume, and total liver/spleen volume ratio in the case group were lower than those in the control group, and the differences were statistically significant (P<0.05). The spleen volume and left lateral lobe volume in the case group were higher than those in the control group, and the difference was statistically significant (P<0.05 ). The AUC values under ROC curve of liver/spleen volume and liver volume were 0.902 and 0.837, respectively. MSCT examination of liver volume and spleen volume has high clinical reference value for judging liver cirrhosis and liver reserve function.

Colonoscopic Manifestations of Colorectal Polyps and Its Carcinogenesis Relationship with TG and NLR

SHI Yuan, YANG Qian, ZHANG Yi, WANG Yalei

2022, 40(2):  382-386.  DOI: 10.7517/issn.1674-0475.210919

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This study investigated the colonoscopy and pathology of colorectal polyps, and its correlation with triglyceride (TG), neutrophil lymphocyte ratio (NLR). 422 patients with colorectal polyps were selected as the subjects, the colonoscopic manifestations and pathological distribution characteristics of the patients were analyzed, and the differences of TG, NLR and other indicators between patients with polyp canceration and non polyp canceration were analyzed. A total of 1084 polyps were detected, most of which were sessile polyps. Pathology showed more adenomatous polyps. The age of polyp canceration group was significantly higher than that of non polyp canceration group (P<0.05). The total cholesterol (TC), triglyceride (TG), serum uric acid (SUA) and NLR were significantly higher than that in non polyp canceration group (P<0.05), while platelet count (PLT) was significantly lower than that in non polyp canceration group (P< 0.05). Logistic regression analysis showed that age, TG and NLR were the influencing factors of polyp carcinogenesis (P<0.05). Colorectal polyps are mainly sessile polyps, and adenomatous polyps are the main pathological types. The canceration of polyps are affected by age, TG and NLR levels.

Diagnosis of MRI in Ulnar Impingement Syndrome and Its Consistency with Wrist Arthroscopy

SUN Wei, HAN Youdong

2022, 40(2):  387-391.  DOI: 10.7517/issn.1674-0475.210922

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The purpose of this article is to investigate the diagnosis of magnetic resonance technology (MRI) in ulnar impingement syndrome and its consistency with wrist arthroscopy, so as to provide reference for clinical diagnosis and treatment. All 92 patients with ulnar impingement syndrome (UIS) underwent MRI and wrist arthroscopy. Statistics on the diagnosis of UIS by wrist arthroscopy, the consistency of the degree of cartilage damage in the MRI diagnosis of UIS with wrist arthroscopy, and the degree of triangular fibrocartilage disc damage in the diagnosis of UIS The accuracy rate of MRI showed that there were 56 cases (60.87%) of ulnar positive variants in 92 UIS patients, 16 cases of ulnar negative variants (17.39%), and 20 cases of ulnar neutral variants (21.74%). The diagnostic accuracy rate of UIS was 96.74%. The Kappa value of MRI diagnosis of UIS cartilage damage and wrist arthroscopy was 0.918 (P<0.05). The overall accuracy of MRI diagnosis of the damage of the triangular fibrocartilage disc in UIS was 93.48%. It can be seen that MRI can accurately detect the damage and extent of the triangular fibrocartilage disc, the ulnar side of the lunar bone, the ulnar head, and the radial side of the triangle bone in the early stage. The diagnosis of cartilage damage is consistent with the wrist arthroscopy.

Study on the Efficacy of Laparoscopy Combined with Ultrasound-guided Percutaneous Microwave Ablation in the Treatment of Hysteromyoma

ZHAN Xiaoshuang, WANG Ying

2022, 40(2):  392-396.  DOI: 10.7517/issn.1674-0475.210927

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This study investigated the efficacy and safety of laparoscopy combined with ultrasound-guided percutaneous microwave ablation in the treatment of uterine leiomyoma. A total of 140 patients with uterine fibroids were selected as research objects, including 244 fibroids. All patients were given laparoscopic combined ultrasound-guided percutaneous microwave ablation treatment. Among 244 uterine fibroids, 151 were completely ablated, accounting for 61.89%. The volume of leiomyoma at 1 month and 3 months after operation was significantly lower than that before operation (P<0.05). Before surgery, the echo characteristics of 244 uterine fibroids were mainly hypoechoic, and the echo of uterine fibroids 3 months after surgery was mainly homogeneous iso-echo or hyperechoic (P<0.05). The symptom severity (SSS) score at 1 month and 3 months after operation was lower than that before operation (P<0.05), and the score of health-related quality of life (HRQL) was higher than that before operation (P<0.05). Adverse reactions were mainly mild pain in ablation zone, vaginal discharge and fever. Endoscopic combined with ultrasound-guided percutaneous microwave ablation has good efficacy and safety in the treatment of uterine fibroids and is worthy of clinical use.

A Comparative Study of Lung Ultrasound and HRCT in the Diagnosis of Interstitial Lung Disease

YOU Shuhong, PENG Guiping, TAO Rong

2022, 40(2):  397-402.  DOI: 10.7517/issn.1674-0475.210932

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This paper discussed the value of pulmonary ultrasound in the diagnosis of interstitial diseases, and analyzed the difference between ultrasonography and high-resolution CT (HRCT) and its clinical application value. All patients received lung ultrasonography and HRCT examination.A total of 127 patients with connective tissue diseases were selected for clinical research. According to the clinical diagnosis results, the patients were divided into the interstitial lung disease group (97 cases) and the non-interstitial lung disease group (30 cases). The detection rate of B-line, pleural thickening and pleural surface roughness in the interstitial lung disease group was significantly higher than that in the non-interstitial lung disease group, and the difference was statistically significant (P<0.05). The sensitivity of lung ultrasound in diagnosing patients with interstitial lung disease was 85.57%, the specificity was 80.70%,and the AUC value was 0.831.The sensitivity of HRCT in the diagnosis of patients with interstitial lung disease was 93.81%, the specificity was 87.72%, and the AUC value was 0.908.The value of lung ultrasonography in diagnosing interstitial diseases is similar to that of HRCT, but it has the advantages of simple operation and good consistency in evaluating the condition of patients.

Relationship between CT Imaging Features, Condition and Curative Effect of Patients with Lumbar Disc Herniation

GUAN Guoyi, MA Le

2022, 40(2):  403-408.  DOI: 10.7517/issn.1674-0475.211104

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This study investigated the relationship between CT imaging features, symptom severity and curative effect in patients with lumbar disc herniation. 120 patients with lumbar disc herniation treated were selected. All patients were given conservative treatment. Logistic regression analysis showed that the type of nucleus pulposus protrusion, the size of frontal protrusion, the size of horizontal protrusion and the way of nerve root compression were the influencing factors of moderate and severe patients (P<0.05). The age of effective patients was lower than that of ineffective patients (P<0.05). The patients with moderate and severe, nucleus pulposus free spinal canal, frontal protrusion c-d domain, horizontal protrusion 3-4 areas, nerve root compression or adhesion, and dural sac compression and displacement of patients with ineffective treatment were higher than those with effective treatment (P<0.05). In patients with lumbar disc herniation, CT imaging features are related to severity and treatment effect.

Value of SMI Combined with UE in Differential Diagnosis of Benign and Malignant Thyroid Nodules

CAI Shuyun, LI Wei

2022, 40(2):  409-413.  DOI: 10.7517/issn.1674-0475.211102

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The purpose of this study was to investigate the value of superb micro-vascular imaging (SMI) combined with ultrasound elastography (UE) in the differential diagnosis of benign and malignant thyroid nodules. Ultrasound, SMI and UE examination were performed in patients with thyroid nodules and the diagnosis results were analyzed. Among the 122 nodules in 80 patients, The proportion of malignant nodules with blood flow classification of grade Ⅱ to Ⅲ by SMI was significantly higher than that of benign nodules (P<0.05). The proportion of malignant nodules with regular shape and internal cystic lesions was significantly lower than that of benign nodules (P<0.05), while the proportion of unclear boundary, aspect ratio ≥1, hypoechoic and internal calcification was significantly higher than that of benign nodules (P<0.05). The strain rate ratio ≥3.79, and the proportion of elastic score 4-5 of malignant nodules were significantly higher than those of benign nodules (P<0.05). The sensitivity and negative predictive value of SMI combined with UE in the diagnosis of thyroid malignant nodules were significantly higher than that of color ultrasound combined with UE (P<0.05). SMI combined with UE can improve the differentiation ability of benign and malignant thyroid nodules, which is worthy of clinical use.

Significance of High Frequency Ultrasound in Differential Diagnosis of Benign and Malignant Breast Micronodules

DAI Nina, ZHANG Wenjun

2022, 40(2):  414-417.  DOI: 10.7517/issn.1674-0475.210806

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The purpose of this study was to explore the significance and value of high frequency ultrasound in the differential diagnosis of benign and malignant breast nodules. The general data of 122 patients with breast micronodules treated were analyzed retrospectively. All the patients were diagnosed by high frequency ultrasound. The blood flow status, blood flow parameters and two-dimensional sonographic features of benign and malignant nodules were analyzed. The diagnostic value of high frequency ultrasound was analyzed. The results showed that the proportion of grade Ⅰand grade Ⅲ of malignant nodules was lower than that of benign nodules (P<0.05), and the blood flow resistance index of malignant nodules was higher than that of benign nodules (P<0.05). The negative predictive value, sensitivity, positive predictive value, specificity and accuracy of high-frequency ultrasound in the diagnosis of malignant tiny breast nodules were 95.0%, 85.0%, 89.5%, 96.6% and 93.7%, respectively. There was no significant difference compared with pathological diagnosis (P>0.05). This study shows that high-frequency ultrasound can accurately diagnose benign and malignant breast small nodules by blood flow state and parameters, and has high accuracy and specificity. After using "BI-RADS" classification, the accuracy of high frequency ultrasound in the diagnosis of breast lesions has been significantly improved.

The Relationship between Graft, Surrounding Structure and Knee Stability after Reconstruction of ACL Injury was Analyzed by Three-dimensional CT Combined with MRI

JIN Lidan, SHEN Ruitian

2022, 40(2):  418-423.  DOI: 10.7517/issn.1674-0475.210916

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The purpose of this article was to explore the correlation between the grafts, surrounding structures and the stability of the knee joint after reconstruction of the knee joint anterior cruciate ligament (ACL) injury caused by the CT three-dimensional reconstruction technology combined with MRI. According to the stability of the knee joint after the operation. A total of 238 patients with knee ACL injury caused by exercise were divided into unstable group (31 cases) and stable group (207 cases). Through comparative analysis, it was found that the positive rate of graft continuity, the rate of graft loosening, the positive rate of screw, the positive rate of bone around the tunnel, and the positive rate of intra-articular cavity of the situation in the unstable 418group was higher than those of the stable group. The postoperative graft signal strength, tibia anterior movement, and Blumensaat angle in the unstable group were higher than those in the stable group, while the ACL angle was lower than that in the stable group (P<0.05). Graft continuity, graft orientation, screws, bone around the tunnel, intra-articular conditions, postoperative graft signal intensity, postoperative tibial anterior movement, postoperative ACL angle, and postoperative Blumensaat angle were all the influencing factors of postoperative knee instability after reconstruction (P<0.05). The area under the curve (AUC) of the Logistic regression model for predicting postoperative knee instability was 0.909. It shows that CT three-dimensional reconstruction technology combined with MRI has a significant correlation with the stability of knee joint in the detection of the postoperative graft status and surrounding structures in patients with knee ACL, and has a certain value in predicting the stability of knee joint.

The Study of Bone Mineral Density and Necrotic Volume Ratio in Evaluating the Curative Effect of Femoral Head Necrosis

LIU Huijuan, GUO Ke, DUAN Xiaobo

2022, 40(2):  424-428.  DOI: 10.7517/issn.1674-0475.210820

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The purpose of this study was to investigate the value of bone mineral density and necrosis volume ratio in the evaluation of postoperative curative effect of patients with femoral head necrosis. A total of 108 patients with femoral head necrosis were selected as the research object. According to follow-up, the patients were divided into disease progression group (n=44) and non-progression group (n=64). Bone density was measured by dual-energy X-ray and necrosis volume was measured by MRI. The clinical data of the two groups were compared. In the progressive group, the age, volume ratio of necrosis and the location of necrosis area in the weight-bearing area were significantly higher than those in the non progressive group (P<0.05), while the increased value of bone mineral density in the necrosis area was significantly lower than that in the non progressive group (P<0.05). Logistic regression analysis showed that the influencing factors of the disease progression of femoral head necrosis were the necrosis volume ratio, the location of the necrosis area in the weight-bearing area and the increased bone mineral density in the necrosis area (P<0.05). The area under the ROC curve of the necrosis volume ratio and the increased bone mineral density in the necrosis area for predicting disease progression were 0.808 and 0.849, respectively (P<0.05). The volume ratio of necrosis, the location of necrosis area and the increased value of bone mineral density in the necrosis area affect the postoperative curative effect of patients with femoral head necrosis, have certain application value in predicting curative effect.

Analysis of the Protective Effect of Amino Acids on the Muscle Injury of Aerobics Athletes after Endurance Exercise Based on CT Image

LI Jing, HU Jianping, ZHANG Yuanyuan

2022, 40(2):  429-433.  DOI: 10.7517/issn.1674-0475.210921

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This article aims to determine the protective effect of amino acid supplementation on the muscle damage of aerobics athletes during endurance exercise through CT images. Twelve aerobics athletes were randomly assigned to the amino acid (AA) group or the placebo (P) group, 6 in each group, received 4 weeks (T2-T5) full-body endurance training. CT images were used to analyze the muscle injury before exercise (T1) and after weekly training (T2-T5). The results showed: (1) Compared with the P group, the muscle damage in the AA group was greatly improved. (2) Compared with T1, 1 RM squat and 1 RM bench press decreased at T2 in P group, while 1 RM squat and 1 RM bench press increased slightly at T3 in both AA and P groups. At T4 and T5 Significant increase (P<0.05). (3) Serum creatine kinase and uric acid increased significantly in P group at T2, serum sex hormone binding globulin and serum 22-kDa growth hormone levels at T2-T5 increased significantly, and hemoglobin concentration 429 decreased, while the changes in AA group were not significant. (4) The content of total testosterone in P group was significantly reduced at T4, and the content of AA group was higher than that of P group at T2-T4. In conclusion, aerobics athletes supplemented with amino acids during endurance exercise has a certain protective effect on their muscle damage.

Diagnostic Analysis of Coronary CTA in Patients with Coronary Stenosis and Bifurcation Lesions

MA Teng, HONG Fangyan, ZHAO Qiang

2022, 40(2):  434-438.  DOI: 10.7517/issn.1674-0475.210929

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The study explored the diagnostic value of coronary CT angiography (CTA) in patients with coronary stenosis and bifurcation lesions. A total of 84 patients with coronary heart disease who underwent CTA examination and coronary angiography (CAG) for clinical research. The results of CTA and CAG examinations of each segment of the coronary artery and the left coronary artery were compared.Using CAG as the diagnostic gold standard.The diagnostic value of CTA for coronary artery stenosis, coronary artery disease with different degrees of stenosis, and left coronary artery bifurcation disease were calculated. The sensitivity of CTA in diagnosing coronary artery stenosis in patients with coronary heart disease is 89.61%, and the specificity is 91.73%. The consistency of the degree of coronary artery stenosis in patients with coronary heart disease diagnosed by CTA and the CAG result Kappa value was 0.761, P<0.05. The sensitivity and specificity of left coronary artery bifurcation lesions in patients with coronary heart disease diagnosed by CTA was 86.36% and 90.00%. As a non-invasive examination method, CTA has high diagnostic value for coronary artery stenosis and bifurcation lesions in patients with coronary heart disease, and has high consistency with CAG results.

Study on the Time-intensity Curve Parameters of Contrast-enhanced Ultrasound in Evaluating the Preoperative Staging of Bladder Cancer

CHEN Yuna, ZHOU Meijuan, FAN Na

2022, 40(2):  439-442.  DOI: 10.7517/issn.1674-0475.210905

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The purpose of this study was to discussed the value of contrast-enhanced ultrasound (CEUS) in preoperative staging of ladder cancer. A total of 90 patients with bladder cancer treated were selected for contrast-enhanced ultrasonography and compared with the postoperative pathological results. The Kappa value of preoperative T-stage of contrast-enhanced ultrasound and postoperative pathological results was 0.699 (P<0.05), and the diagnostic accuracy was 76.67%. The Kappa value of preoperative N-stage of contrast-enhanced ultrasound and postoperative pathological results was 0.705 (P<0.05), and the diagnostic accuracy was 84.40%. The time from peak to one half (TPH) of low-grade bladder cancer was significantly lower than that of higher-grade bladder cancer (P<0.05), and the semi-descending slope (DS) was significantly higher than that of higher-grade bladder cancer (P<0.05). The area under ROC curve of TPH and DS for the differentiation of low-grade bladder cancer were 0.766 and 0.709 (P<0.05). The sensitivity of TPH and DS were 72.90% and 62.50%, and the specificity were 71.40% and 76.20%, respectively. Contrast-enhanced ultrasound has a good application value in preoperative evaluation of bladder cancer.