IMAGING SCIENCE AND PHOTOCHEMISTRY ›› 2022, Vol. 40 ›› Issue (2): 269-274.DOI: 10.7517/issn.1674-0475.210918

• Review and Articles • Previous Articles     Next Articles

Analysis of the Value of 3D-PDU Combined with Serum to Detect Central Placenta Previa and Placenta Accreta

SHEN Jie1, REN Qing2, LIAO Weiwei1, ZHENG Weixiu1, DENG Senling1, LIN Yuan1   

  1. 1. Hainan West Central Hospital, Danzhou 571700, Hainan, P. R. China;
    2. Shanghai Ninth People's Hospital(Medical Union of Hainan West Central Hospital), Shanghai 200011, P. R. China
  • Received:2021-09-18 Online:2022-03-15 Published:2022-03-08

Abstract: This study investigated the value of three-dimensional power Doppler ultrasound (3D-PDU) combined with serum in detecting central placenta previa and placenta implantation. Fifty-two patients with central placenta previa (CPP) and placenta accreta (PA) were selected as the PA group, and 52 patients with CPP without PA during the same period were selectedas the PA group. Ultrasound examination of 52 normal pregnant women with placenta attached to the anterior uterine wall was the control group. All were examined by 3D-PDU, and the levels of blood alpha-fetoprotein (AFP) and soluble vascular endothelial growth factor receptor 1 (SFlt-1) were detected. After analysis, it was found that the levels of VI, FI, VFI, and serum AFP in the PA group were higher than those in the PA-free group and the control group, and the SFlt-1 levels were lower than those in the PA-free group and the control group (P<0.05). The AUC of VI, FI, VFI, AFP and SFlt-1 combined to diagnose CPP and PA was greater than the AUC diagnosed by each index alone, and the sensitivity and specificity of the combined diagnosis are 90.59% and 76.47%, respectively. The incidence of PA in patients with high expression of VI, FI, VFI, and serum AFP is higher than that of 269those with low expression, and SFlt-1 is low The incidence of PA in expressers was higher than that in high expressers (P<0.05). The use of 3D-PDU combined with blood AFP and SFlt-1 level diagnosis is expected to provide an effective way for clinical diagnosis and treatment of CPP and PA.

Key words: three-dimensional power Doppler ultrasound, alpha-fetoprotein, soluble vascular endothelial growth factor receptor 1, central placenta previa, placenta accreta