Abstract: This article aims to explore the correlation between CT imaging findings and histopathological grading of lung adenocarcinoma.A retrospective collection of 149 patients with pathologically confirmed lung adenocarcinoma, according to the grading standard, the patients were divided into a moderately well-differentiated group (level Ⅰ and Ⅱ), a poorly differentiated group (level Ⅲ), and the relationship between CT imaging manifestations of lung adenocarcinoma and postoperative pathological grading was analyzed. Results: (1) The smallest and largest diameters of the tumors in the moderately well-differentiated group were significantly lower than those in the poorly differentiated group (P<0.05). (2) 47.4% of the tumor marginal signs in the moderately well-differentiated group showed lobular signs, while 68.5% in the poorly differentiated group, there was a significant difference between the two group (P<0.01). (3) 26.3% of the moderately differentiated group has ground glass shadow, and 3.7% of the poorly differentiated group, there was a significant difference between the two group (P<0.01). In short, the CT appearance of lung adenocarcinoma is significantly correlated with its pathological grade.

Key words: lung adenocarcinoma, computed tomography (CT), pathological grade, correlation