Abstract: This study explored the application value of 320-slice CT in the interventional therapy for congenital heart disease (CHD). A retrospective study was carried out in 66 patients with CHD, including 33 cases of atrial septal defect (ASD) and 33 cases of ventricular septal defect (VSD). All patients underwent transthoracic echocardiography (TTE) and 320-slice CT four-dimensional volume dynamic imaging (4D-CCTA) before and after interventional occlusion surgery. The results showed that the difference between the maximum diameter of ASD, VSD and the waist diameter (POS) of the occluder measured by preoperative TTE and 4D-CCTA was smaller than the difference measured by TTE (P<0.05). The maximum diameter of ASD and VSD measured by preoperative TTE and 4D-CCTA both had a good correlation with POS and the selected type of occluder (P<0.05), and the latter had a higher correlation. The postoperative EF, EDVI, ESVI, SVI, and CI of CHD patients measured by 4D-CCTA were lower than those data measured by TTE (P<0.05). It can be seen that 320-slice CT could accurately measure the size of preoperative ASD and VSD, and total interval length of CHD patients, which could be helpful to guide doctors in selecting the type 615of occluder, and accurately evaluate the left ventricular function of patients after operation.

Key words: congenital heart disease, 320-slice CT, interventional occlusion surgery, occluder waist diameter, left heart function