Abstract: This study explored the value of echocardiography in the diagnosis of fetal congenital heart disease and the risk factors affecting the onset of congenital heart disease. A retrospective study was conducted, 18987 pregnant women underwent prenatal examination were selected, and 65 families with fetal congenital heart disease (case group) and 130 families with normal fetus (control group) were investigated by questionnaire. The incidence rate of congenital heart disease was 0.43%, the disease types were simple ventricular septal defect, endocardial cushion defect and double outlet of right ventricle; Logistic regression analysis showed that maternal age, history of teratogen exposure during pregnancy, maternal diabetes mellitus, maternal connective disease, adverse pregnancy history, chromosomal abnormalities, early fetal NT value and family history of congenital heart disease were the influencing factors of congenital heart disease (P<0.05). It is concluded that echocardiography has good value in the diagnosis of fetal congenital heart disease, and the incidence of congenital heart disease is affected by maternal age, teratogenic exposure history and other factors.

Key words: echocardiography, fetus, congenital heart disease, diagnostic value, risk factors