IMAGING SCIENCE AND PHOTOCHEMISTRY ›› 2022, Vol. 40 ›› Issue (3): 510-514.DOI: 10.7517/issn.1674-0475.211204

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Application of SMART 3D-SMI in the Differential Diagnosis of Benign and Malignant in TI-RADS 4 Thyroid Nodules

LI Chaoxi, WEN Dehui, LIU Weiliang, LU Haiyong   

  1. The First Affiliated Hospital of Heibei North University, Zhangjiakou 075000, Hebei, P. R. China
  • Received:2021-12-20 Online:2022-05-15 Published:2022-05-27

Abstract: This study investigated the application value of 3-dimensional ultrasound imaging (smart 3D-SMI) in the differential diagnosis of benign and malignant in TI-RADS 4 thyroid nodules. 120 cases of patients (128 nodules) with TI-RADS type 4 nodules were selected and analyzed the diagnostic efficacy of CDFI, 2D-SMI and 3D-SMI for benign and malignant of TI-RADS type 4 nodules. Pathologically confirmed 84 cases benign and 44 cases malignant. TI-RADS had 87 grades 4a, 30 grades 4b and 11 grades 4c, with an accuracy rate of 67.97%. Compared with CDFI, 2D-SMI and 3D-SMI had higher blood flow grades, and detected more grade 3 blood flow. There was no statistically significant difference between 2D-SMI and 3D-SMI grades (P>0.05). There was no significant difference in the blood flow distribution pattern of benign nodules in CDFI, 2D-SMI and 3D-SMI (P>0.05). Compared with CDFI, malignant nodules showed more type Ⅲ in 2D-SMI and 3D-SMI modes (P<0.05). TI-RADS combined with CDFI, 2D-SMI and 3D-SMI respectively in the differential diagnosis of benign and malignant thyroid nodules, compared of the three methods, TI-RADS +3D-SMI had higher sensitivity, accuracy and negative predictive value (P<0.05), and had no significant difference in diagnostic specificity and positive predictive value (P<0.05). SMART 3D-SMI can accurately assess the microvascular spatial distribution and pattern of thyroid TI-RADS 4 nodules.

Key words: thyroid nodule, 3 dimensional ultrasound imaging of microvascular, thyroid imaging report and data system, differential diagnosis