Abstract: This study discussed the value of transvaginal three-dimensional ultrasound in the differential diagnosis of cornual pregnancy and tubal interstitial pregnancy. 55 cases of cornual pregnancy and 60 cases of tubal interstitial pregnancy were selected retrospectively, and compared the differences of ultrasonic image characteristics and quantitative parameters between the two group. The gestational sac bulge, the proportion of intact uterine cavity and the end diastolic velocity (EDV) of trophoblast artery in cornual pregnancy were significantly lower than those in tubal interstitial pregnancy (P<0.05), while the proportion of peripheral myometrium is intact, endometrial wrapping or adjacent, the thickness of peripheral myometrial wrapping of gestational sac and the resistance index (RI) of trophoblast artery were significantly higher than those in tubal interstitial pregnancy (P<0.05). The area under ROC curve of myometrial wrapping thickness around gestational sac, trophoblastic artery EDV combined with trophoblastic artery RI in differentiating cornual pregnancy and tubal interstitial pregnancy was 0.865, P<0.05. The sensitivity, specificity, accuracy, positive predictive value and negative predictive value of transvaginal three-dimensional ultrasonography in differential diagnosis of cornual pregnancy and tubal interstitial pregnancy were higher than 80.00%, transvaginal three-dimensional ultrasound has good application value in the differential diagnosis of cornual pregnancy and tubal interstitial pregnancy.

Key words: cornual pregnancy, tubal interstitial pregnancy, transvaginal three-dimensional ultrasound, differential diagnosis443