Abstract: In this study,the blood supply characteristics of primary hepatic carcinoma (PHC) were observed by CT liver perfusion imaging, and the blood perfusion after tanscatheter arterial chemoembolization (TACE) was evaluated. Seventy patients confirmed as PHC by liver biopsy were selected for TACE treatment, and CT liver perfusion imaging was performed before and after TACE intervention to evaluate the effect, and analyze the value of CT liver perfusion imaging for short-term efficacy in PHC patients. Compared with non-tumor tissues, the hepatic blood flow (HBF), hepatic artery perfusion index (HPI), hepatic artery perfusion (HAP) in tumor active lesions were higher, and the time to peak (TTP) was lower (P<0.05). Compared with ineffective patients, microvascular density (MVD) and vascular endothelial growth factor (VEGF) were lower in effective patients (P<0.05). Compared with the before intervention, HBF, HPI and HAP were lower and TTP was higher after intervention (P<0.05). The AUC of HBF, HPI, HAP and TTP combined diagnosis was 0.940 (P<0.05), and the diagnostic efficiency of short-term efficacy in patients with PHC was higher (P<0.05). CT liver perfusion imaging is helpful in assessing the postoperative blood flow status after TACE in patients with PHC, with high clinical value.

Key words: CT liver perfusion imaging, primary hepatic carcinoma, tanscatheter arterial chemoembolization, blood perfusion