Effect of Yibuweibao Decoction Combined with Ziwu Liuzhu Acupuncture on Treating Chronic Gastritis

doi:10.7517/issn.1674-0475.220405

Abstract

Abstract: This study investigated the effect of Yibuweibao Decoction combined with Ziwu Liuzhu acupuncture on gastroscopic indexes of patients with chronic gastritis. Selected 136 patients with chronic gastritis and divided them into the control group (routine western medicine) and acupuncture drug combination group (plus Yibuweibao Decoction combined with Ziwu Liuzhu acupuncture) according simple random method with principle of 1:1. Pepsinogen subsets, inflammatory factors were compared between the two groups, and the difference of traditional Chinese medicine(TCM)symptom score, quality of life score, the curative effect and safety were observed. After treatment, the total effective rate in the acupuncture drug combination group was significantly higher than that in the control group (P<0.05). The TCM symptoms in the acupuncture and medicine combination group were significantly lower than those in the control group, and the score of quality of life was significantly higher than those of the control group (P<0.05). Pepsinogen II (PGII), Soluble Interleukin-2 Receptor (sIL-2R), Chemokine-1 (MCP-1) and Tumor Necrosis Factor-α (TNF-α) after treatment in the two groups were both lower than before treatment, the PepsinogenⅠ (PGⅠ) and PGⅠ/PGⅡ were higher than before treatment, and the improvement of pepsinogen subsets and inflammatory factors in the acupuncture drug combination group were significantly better than those in the control group (P<0.05). The improvement of gastroscopic symptoms in the acupuncture drug combination group was significantly better than that in the control group (P<0.05). There was no significant difference in adverse reactions between the two groups (P>0.05). Yibuweibao decoction combined with Ziwu Liuzhu acupuncture in the treatment of chronic gastritis can regulate the expression of pepsinogen subsets and inflammatory factors, and also can improve the performance of the symptoms under gastroscopy, and has high safety.

Key words: Yibuweibao Decoction, Ziwu Liuzhu acupuncture, chronic gastritis, pepsinogen subgroup

HAO Jie, HUANG Yunman, HUO Yongli, LI Bolin, SUN Runxue, YIN Lu, CHEN Xian. Effect of Yibuweibao Decoction Combined with Ziwu Liuzhu Acupuncture on Treating Chronic Gastritis[J]. IMAGING SCIENCE AND PHOTOCHEMISTRY, 2022, 40(5): 1158-1163.

References

[1] IShikura N, Usui Y, Ito H, et al. Helicobacter pylori (HP) infection alone, but not HP-induced atrophic gastritis, increases the risk of gastric lymphoma:A case-control study in Japan[J]. Annals of Hematology, 2019, 98(8):1981-1987.
[2] El-Zimaity H, Riddell R H. Beyond Helicobacter:dealing with other variants of gastritis-an algorithmic approach[J]. Histopathology, 2021, 78(1):48-69.
[3] 熊霞军, 胡志希, 黄淑敏, 等. 基于数据挖掘的治疗慢性胃炎中药复方用药规律研究[J]. 现代中医临床, 2021, 28(4):18-22, 28.
[4] 张健强, 赵征宇, 张薇, 等. 基于CiteSpace的子午流注针法知识图谱分析[J]. 世界科学技术-中医药现代化, 2020, 22(8):2727-2735.
[5] 中华医学会消化病学分会. 中国慢性胃炎共识意见(2017年, 上海)[J]. 中华消化杂志, 2017, 37(11):721-738.
[6] 张声生, 唐旭东, 黄穗平, 等. 慢性胃炎中医诊疗专家共识意见(2017)[J]. 中华中医药杂志, 2017, 32(7):3060-3064.
[7] 吴玲, 王小丹, 刘玉梅, 等. SF-36量表用于老年人群信度及效度研究[J]. 中国老年学杂志, 2008, 28(11):1114-1115.
[8] 吉跃进, 李红晓, 陆为民. 国医大师徐景藩从血瘀论治慢性胃脘痛经验[J]. 中华中医药杂志, 2020, 35(1):179-182.
[9] 刘明晖, 赵树华. 赵树华治疗胃脘痛用药规律研究[J]. 中国医药导报, 2019, 16(33):120-124.
[10] 李琛瑛, 王毅, 罗云, 等. 子午流注针法相关文献研究分析[J]. 吉林中医药, 2018, 38(4):451-454.
[11] 何敏, 卢家春, 陆必波, 等. "个体化计时"子午流注针法治疗老年慢性胃炎临床研究[J]. 上海针灸杂志, 2016, 35(6):656-658.
[12] 刘新桥, 王玲. 正气散加减治疗慢性胃炎对患者生活质量、炎性因子水平的影响[J]. 中国中药杂志, 2019, 44(1):181-185.
[13] 杨梦, 胡志希, 李欣春, 等. 袁肇凯教授治疗慢性非萎缩性胃炎的用药规律探究[J]. 湖南中医药大学学报, 2020, 40(10):1272-1275.
[14] 姜辉, 顾胜龙, 张玉婷, 等. 黄芪化学成分和药理作用研究进展[J]. 安徽中医药大学学报, 2020, 39(5):93-96.
[15] 蔡兴航, 孙晓春, 孙安敏, 等. 党参茎叶总皂苷提取工艺及其抗氧化活性研究[J]. 中国农学通报, 2018, 34(26):146-151.
[16] 崔鹤蓉, 王睿林, 郭文博, 等. 茯苓的化学成分、药理作用及临床应用研究进展[J]. 西北药学杂志, 2019, 34(5):694-700.
[17] 王晶, 张世洋, 盛永成, 等. 白术治疗胃肠道疾病药理作用研究进展[J]. 中华中医药学刊, 2018, 36(12):2854-2858.
[18] 王阳, 范潇晓, 杨军, 等. 木香的萜类成分与药理作用研究进展[J]. 中国中药杂志, 2020, 45(24):5917-5928.
[19] 黄秀芳, 庾国桢, 童晶晶. 基于网络药理学分析陈皮的药理作用机制[J]. 中成药, 2019, 41(12):3038-3045.
[20] 雷林, 肖锟钰, 瞿领航, 等. 谷芽的本草考证[J]. 中国实验方剂学杂志, 2020, 26(10):197-204.
[21] 樊宇靖, 蓝宇, 贾纯增. 血清胃蛋白酶原检测在慢性胃炎患者的诊断和随访中的临床意义[J]. 中国实验诊断学, 2018, 22(4):596-598.
[22] 倪冰颖, 鲍洛文, 黄秋菊, 等. 慢性萎缩性胃炎并幽门螺杆菌感染患者吹气定量测定值与G-17、IL-32、sIL-2R水平及胃镜下病理变化的关系[J]. 世界华人消化杂志, 2021, 29(14):816-824.
[23] 方明, 张国庆. 香砂养胃汤联合替普瑞酮胶囊对慢性浅表性胃炎患者外周血胃肠激素、T淋巴细胞亚群、IL-8、IL-32、MCP-1的影响[J]. 中药材, 2020, 43(11):2812-2816.
[24] 胡掌朝, 安俊丽, 程帅师, 等. 慢性萎缩性胃炎患者Hp感染与IL-8、PCT、TNF-α表达水平及严重程度的关系分析[J]. 热带医学杂志, 2021, 21(6):731-734.