Abstract: The objective of this study was to compare the postoperative analgesic effects of ultrasound-guided erector spinae plane block (ESP) and ultrasound-guided transverse abdominis plane block (TAP) on patients undergoing radical resection of colorectal cancer. A total of 120 patients who underwent radical resection of colorectal cancer were selected as the research objects, and divided into the control group and the study group according to the random number table method with 60 cases in each group. The control group underwent ultrasound-guided TAP, the study group underwent ultrasound-guided ESP, and the heart rate, mean arterial pressure, visual analogue scale (VAS) score, Ramsay sedation score, stress-reaction questionnaire (SRQ) score, drug dose, recovery index detection, and complication response were detected in the two groups. Compared with T₀,T₁, and T₂, the heart rate and mean arterial pressure of the two groups increased at T₃, but the study group was lower than the control group (P<0.05). Compared with the control group, the VAS scores of the patients in the study group were lower at 2 h, 4 h, 8 h, and 12 h after the operation, and the Ramsay sedation score was higher (P<0.05). Compared with preoperative, the scores of emotional response, physical response and behavioral response in the two groups decreased at 48 h after surgery, and the scores in the study group were lower than those in the control group (P<0.05). Compared with the control group, the patients in the study group had less dosage of remifentanil and propofol, the recovery time, wake time and tracheal extubation time were shorter, and the incidence of complications was lower (P<0.05). Compared with ultrasound-guided TAP, ESP has better postoperative analgesia, which can reduce the incidence of complications and speed up the postoperative recovery of patients.

Key words: colorectal cancer, ultrasound guidance, erector spinae plane block, transverse abdominis plane block, analgesia