Abstract: 2, 6-Dimethyl-3, 5-carboethoxy-1, 4-Dihydropyridine was synthesized and its photochemical reaction under UV (366 nm) irradiation was studied. The results show that the main product is 2, 6-Dimethyl-3, 5-Dicarboethoxy-pyridine (95%) and a small amount of Di-π Methane photorearrangement product, 1, 3-Dimethyl-2-aza-4, 5-Dicarboe-thoxy-bicyclo-(3, 1, 0,)-hexene-3 (5%), is obtained.