Advances of Cancer Combination Therapy Based on Upconversion Nanoparticles and Photodynamic Therapy

doi:10.7517/j.issn.1674-0475.2016.04.297

Abstract

Abstract:

Photodynamic therapy(PDT), a non-invasive treatment modality, has been widely used clinicallyagainst many types of cancers. However, its efficacy is heavily limited by the low tissue penetration depth of the UV-visible irradiation. Lanthanide-doped upconversion nanoparticles (UCNPs), which can convert near-infrared light to UV-visible light, have been used successfully to improve PDT activities of traditional photosensitizers. Recently, the combination therapy based on UCNPs-PDT is drawing increasing attention, and the related advances as well as perspectives have been presented in this review.

Key words: photodynamic therapy, upconversion nanoparticles, combination therapy

CHEN Yumeng, JIANG Guoyu, WANG Xuesong. Advances of Cancer Combination Therapy Based on Upconversion Nanoparticles and Photodynamic Therapy[J]. Imaging Science and Photochemistry, 2016, 34(4): 297-311.

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