Comparative Study on MR Characteristics and Risk Factors between Young Patients and Middle-aged and elderly Patients with Acute Ischemic Stroke and the Value of Prevention

doi:10.7517/issn.1674-0475.191224

Abstract

Abstract: In this paper, the is risk factors and MR characteristics of acute cerebral infarction in young and middle-aged and elderly were studied, and it is value in clinical diagnosis, treatment and prevention was discussed. To compare and analyze the medical records and imaging data of the young group and the middle-aged and elderly group.The results showed that the most common risk factors were hypertension, hypertriglyceridemia and smoking. The incidence of hypertension, diabetes and hypercholesterolemia in the middle-aged and elderly patients with acute cerebral infarction was significantly higher than that in the young group (P<0.05); the incidence of hypertriglyceridemia and smoking in the young group was significantly higher middle-aged and elderly group (P<0.05). The difference between the two groups was statistically significant in the normal rate of brain MRA and the abnormal rate of multiple vessels (P<0.05); there was no statistical difference in lesion size and number of lesions, and between various parts of acute cerebral infarction (P>0.05).

Key words: acute ischemic stroke, young, middle-aged and elderly, MR, risk factors

WEI Julin, ZHAO Zhixiong. Comparative Study on MR Characteristics and Risk Factors between Young Patients and Middle-aged and elderly Patients with Acute Ischemic Stroke and the Value of Prevention[J]. Imaging Science and Photochemistry, 2020, 38(4): 684-689.

References

[1] Bettina V S, Jukka P, Ulrike G, et al. Lifestyle risk factors for ischemic stroke and transient ischemic attack in young adults in the stroke in young fabry patients study[J]. Stroke, 2012,44(1):119.
[2] 中华医学会神经病学分会脑血管病学组急性缺血性脑卒中诊治指南撰写组.中国急性缺血性脑卒中诊治指南2010[J].中华神经科杂志, 2010,2(4):50-59.
[3] Enrico F, Schulz U G R, Rothwell P M. Systematic review of methods and results of studies of the genetic epidemiology of ischemic stroke[J]. Stroke, 2004,35(1):212-227.
[4] Meschia J F, Cheryl B, Bernadette B A, et al. Guidelines for the primary prevention of stroke:A statement for healthcare professionals from the american heart association/american stroke association[J]. Stroke, 2014,45(12):3754-3832.
[5] Furie K L, Jayaraman M V. 2018 guidelines for the early management of patients with acute ischemic stroke[J]. Stroke, 2018,49(3):509-510.
[6] 冯中全,洪斌,钱伟军,等.青年急性脑梗死的MRA特点及其临床价值[J].磁共振成像,2016,7(6):428-432.
[7] 付伦娇,罗春红,苏斌儒,等.青中年脑梗死与老年脑梗死危险因素比较分析[J].中国实用神经疾病杂志, 2016,19(20):103-105.
[8] 王云霞,卢祖洵,张蕲,等.中国青年脑卒中发病危险因素的Meta分析[J].中国全科医学, 2010,13(3):254-257.
[9] Ploubidis G B, Mathenge W, Stavola B D, et al. Socioeconomic position and later life prevalence of hypertension,diabetes and visual impairment in Nakuru, Kenya[J]. International Journal of Public Health, 2013,58(1):133-141.
[10] Rutten-Jacobs L C A, Maaijwee N A M, Arntz R M, et al. Long-term risk of recurrent vascular events after young stroke:the future study[J]. Annals of Neurology, 2013,74(4):592-601.
[11] Murphy S J, Mccullough L D, Smith J M. Stroke in the female:role of biological sex and estrogen[J]. ILAR Journal, 2004,45(2):147-159.
[12] 刘颖颖,韩有泽,王晔,等.青年缺血性脑卒中的病因及危险因素研究现状[J].卒中与神经疾病, 2017,24(4):371-374.
[13] Ojha R, Huang D, An H, et al. Distribution of ischemic infarction and stenosis of intra- and extracranial arteries in young chinese patients with ischemic stroke[J]. BMC Cardiovascular Disorders, 2015,15(1):158.
[14] Jiang H, Lun Y, Wu X Y, et al. Association between the hypomethylation of osteopontin and integrin β3 promoters and vascular smooth muscle cell phenotype switching in great saphenous varicose veins[J]. International Journal of Molecular Sciences, 2014,15(10):18747-18761.
[15] 张立,刘悦.中青年脑梗死的临床特点及危险因素研究进展[J].临床误诊误治, 2006,19(7):8-9.
[16] 张振华,杨潮萍,刘秀丽,等.青老年脑梗死危险因素与影像学特点的回顾性研究[J].中国急救医学, 2015,35(S2):191-192.
[17] Park W B, Cho J S, Shin S D, et al. Comparison of epidemiology, emergency care, and outcomes of acute ischemic stroke between young adults and elderly in korean population:a multicenter observational study[J]. Journal of Korean Medical Science, 2014,29(7):985-991.
[18] 冯中全,洪斌,钱伟军,等.青年急性脑梗死的MRA特点及其临床价值[J].磁共振成像, 2016,7(6):428-432.
[19] 李振华,杨清成,张建刚,等.青年与中老年脑梗死的对比研究[J].中国卒中杂志, 2016,11(9):743-746.
[20] 李秀明,明敬峰,王娜,等.不同脑血管供血部位新发脑梗死危险因素的差异性分析[J].实用医学杂志, 2016,32(19):3245-3248.