Progress in Research on the Preparation of Gadolinium-doped Carbon Dots and Their Bimodal Imaging

doi:10.7517/issn.1674-0475.200401

Abstract

Abstract: Fluorescence-magnetic resonance imaging (MRI) dual-modal molecular probes, which breaks through the limitation of single molecular imaging probes in terms of sensitivity and soft tissue resolution, has attracted tremendous attention in the fields of diagnosis and treatment. Gadolinium-doped carbon dots (Gd-CDs) is a typical fluorescence-MRI dual-modal molecular probe. With excellent optical properties, good MRI capability and low toxicity, Gd-CDs has a wide application prospect in tumor targeting imaging and treatment monitoring. This work summarizes the research status of the preparations, performance, and applications of Gd-CDs in bimodal imaging. Present problems and prospects are also put forward.

Key words: fluorescence imaging, magnetic resonance imaging, dual-modal molecular probes, gadolinium-doped carbon dots

MA Yihua, CHEN Lin, YANG Yongzhen, YU Shiping, SU Xiuqin. Progress in Research on the Preparation of Gadolinium-doped Carbon Dots and Their Bimodal Imaging[J]. Imaging Science and Photochemistry, 2020, 38(5): 763-770.

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