MSCT to Evaluate the Efficacy of HFNC in Patients with AECOPD Complicated with Mild Type Ⅱ Respiratory Failure

doi:10.7517/issn.1674-0475.221008

Abstract

Abstract: This study investigated the value of multi-slice spiral CT (MSCT) in evaluating the effect of high-flow nasal cannula oxygen therapy (HFNC) in patients with acute exacerbation of chronic obstructive pulmonary disease (AECOPD) complicated by mild type Ⅱ respiratory failure. Selected 200 patients with AECOPD complicated with mild type Ⅱ respiratory failure and randomly divided them into control group and observation group according to the random number table method, with 100 cases in each group. The control group was treated with basic treatment + conventional oxygen inhalation, while the treatment group was treated with basic treatment +HFNC. Blood gas parameters[arterial partial pressure of oxygen (PaO₂), percutaneous oxygen saturation (SaO₂), arterial partial pressure of carbon dioxide (PaCO₂), pH value, oxygen and index (OI)] were compared between the two groups before and after treatment. MSCT was used to measure the single and whole lung volume (L), emphysema volume (E), pulmonary artery diameter and aortic diameter of the two groups. Color doppler ultrasound was used to detect the changes of right ventricular function indexes[right ventricular end diastolic diameter (RVDD), right ventricular anterior wall (RVAW) and right ventricular ejection fraction (RVEF)]. The results showed that after treatment, the measured values of PaO₂, SaO₂ and OI in the treatment group were higher than those in the control group, while the measured values of PaCO₂ were lower than those in the control group (P<0.05). After treatment the whole lung volume E/L, right lung E/L in the treatment group were lower than those in the control group. After treatment, the measured values of RVEF and RVAW in the treatment group were higher than those in the control group (P<0.05). The study found that patients with AECOPD complicated by mild type Ⅱ respiratory failure treated with HFNC had better effect, and MSCT could be used to observe the improvement of emphysema and pulmonary hypertension before and after treatment.

Key words: multi-slice spiral CT, nasal high-flow oxygen therapy, cute exacerbation of chronic obstructive pulmonary disease, type Ⅱ respiratory failure

ZHAO Hongling, LIANG Jinpai, XIAO Cuijun. MSCT to Evaluate the Efficacy of HFNC in Patients with AECOPD Complicated with Mild Type Ⅱ Respiratory Failure[J]. IMAGING SCIENCE AND PHOTOCHEMISTRY, 2023, 41(1): 114-118.

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