影像科学与光化学 ›› 2022, Vol. 40 ›› Issue (4): 735-740.DOI: 10.7517/issn.1674-0475.220316

• 综述与论文 • 上一篇    下一篇

CCTA诊断左冠脉分叉病变的价值及其危险因素研究

唐运军, 张海林, 杨胜杰   

  1. 河池市人民医院放射科, 广西 河池 547000
  • 收稿日期:2022-03-10 发布日期:2022-07-09
  • 通讯作者: 唐运军

The Value of CCTA in Diagnosing Left Coronary Artery Bifurcation Lesions and Its Risk Factors

TANG Yunjun, ZHANG Hailin, YANG Shengjie   

  1. Department of Radiology, The People's Hospital of Hechi, Hechi 547000, Guangxi, P. R. China
  • Received:2022-03-10 Published:2022-07-09

摘要: 本文探讨螺旋CT冠状动脉造影(CCTA)诊断左冠状动脉分叉病变的临床价值及其危险因素研究。选取接受CCTA、冠脉造影检查的200例冠心病患者的资料进行分析,以冠脉造影结果作为诊断金标准,将患者分为左冠状夹角近段管腔狭窄组(93例)与非狭窄组(107例)。狭窄组患者左冠状动脉夹角与管腔直径、管腔截面积测定值均呈负相关关系(P<0.05)。左冠状动脉夹角诊断左冠状夹角近段管腔狭窄的ROC曲线下面积(AUC)为0.894,诊断灵敏度为81.36%、特异度为83.55%,左冠状动脉夹角临界值为81.3°。患者吸烟、合并高血压、冠心病家族史、血清TG增高、HDL-C增高、hs-CRP增高、FPG增高、左冠状动脉夹角>81.3°是发生左冠状夹角近段管腔狭窄的独立危险因素(P<0.05),血清HDL-C水平增高可降低患者发生左冠状夹角近段管腔狭窄的风险(P<0.05)。采用CCTA检查左冠状动脉夹角对于预测和诊断左冠状夹角近段管腔狭窄具有较高的临床价值,冠心病患者左冠状夹角近段管腔狭窄受到多种因素的影响,其中左冠状动脉夹角增大(>81.3°)可明显增大其风险。

关键词: 螺旋CT冠状动脉造影, 左冠状动脉, 夹角, 危险因素

Abstract: This article investigated the clinical value and risk factors of spiral CT coronary angiography (CCTA) in the diagnosis of left coronary bifurcation lesions. Selected 200 patients with coronary heart disease who received CCTA and coronary angiography for analysis. Taking coronary angiography results as the diagnostic gold standard, the patients were divided into the left coronary angle proximal lumen stenosis group (93 cases) and non-stenosis group (107 cases). In the stenosis group, the included angle of the left coronary artery was negatively correlated with the lumen diameter and the measured value of the lumen cross-sectional area (P<0.05). The area under the ROC curve (AUC) of the left coronary angle in the diagnosis of the proximal lumen stenosis of the left coronary angle was 0.894, the diagnostic sensitivity was 81.36%, the specificity was 83.55%, and the critical value of the left coronary angle was 81.3°. Smoking, combined hypertension, family history of coronary heart disease, increased serum TG, increased HDL-C, increased hs-CRP, increased FPG, and left coronary angle > 81.3° were the independent risk factors (P<0.05) for the occurrence of proximal lumen stenosis in the left coronary angle. Increased serum HDL-C level can reduce the risk of stenosis in the proximal segment of the left coronary angle (P<0.05). The use of CCTA to examine the included angle of the left coronary artery has a high clinical value in predicting and diagnosing the proximal lumen stenosis of the left coronary angle. The proximal lumen stenosis of the left coronary angle in patients with coronary heart disease is affected by many factors, among them the increased included angle of arteries (>81.3°) can significantly increase its risk.

Key words: spiral CT coronary angiography, left coronary artery, included angle, risk factors