影像科学与光化学 ›› 1998, Vol. 16 ›› Issue (2): 105-110.DOI: 10.7517/j.issn.1674-0475.1998.02.105

• 研究快汛 • 上一篇    下一篇

竹红菌素作为激发态氧分子的光敏剂的研究

陈彬, 安静仪, 张曼华, 王波杰   

  1. 中国科学院感光化学研究所, 北京100101
  • 收稿日期:1997-12-23 修回日期:1998-01-05 出版日期:1998-05-20 发布日期:1998-05-20
  • 通讯作者: 王波杰
  • 基金资助:
    国家自然科学基金资项目(批准号:29702008)

THE STUDY OF HYPOCRELLINS AS SENSITIZERS OF EXCITED STATE MOLECULAR OXYGEN

CHEN Bin, AN Jinyi, ZHANG Manhua, WANG Bojie   

  1. Institute of Photographic Chemistry, The Chinese Academy of Sciences, Beijing 100101, P. R. China
  • Received:1997-12-23 Revised:1998-01-05 Online:1998-05-20 Published:1998-05-20

摘要: 近年来,竹红菌素(Hypocrellin A and B,简称HA和HB)及其衍生物在光疗技术上的应用,尤其是在癌症和艾滋病的治疗上的应用,越来越引起人们的重视[1~8].

关键词: 竹红菌素, 激发态氧分子, 光敏剂

Abstract: Hypocrellin A and B were studied as sensitizers of excited state molecular oxygen. Our results indicate that the solvent polarizability and excitation wavelength have no effect on the quantum yield of singlet oxygen when Hypocrellins was used as the sensitizers. Also, we found out that the chemical reactivity of Hypocrellins is from both first and second excited state molecular oxygen. Finally, our results indicate that Hypocrellin is a poor singlet oxygen quencher.

Key words: hypocrellin, excited state molecular oxygen, sensitizer