基于萘酰亚胺的Turn-on型Fe3+荧光探针

doi:10.7517/j.issn.1674-0475.2014.01.084

影像科学与光化学 ›› 2014, Vol. 32 ›› Issue (1): 84-90.DOI: 10.7517/j.issn.1674-0475.2014.01.084

基于萘酰亚胺的Turn-on型Fe³⁺荧光探针

殷丽艳, 陈甜甜, 朱维平

华东理工大学药学院, 上海 200237

收稿日期:2013-12-02 修回日期:2013-12-17 出版日期:2014-01-15 发布日期:2014-01-15
通讯作者: 朱维平
基金资助:
国家自然科学基金项目（21236002）资助

A Turn-on Fluorescent Probe for Fe³⁺ Based on Naphthalimide

YIN Liyan, CHEN Tiantian, ZHU Weiping

School of Pharmacy, East China University of Science and Technology, Shanghai 200237, P. R. China

Received:2013-12-02 Revised:2013-12-17 Online:2014-01-15 Published:2014-01-15

摘要/Abstract

摘要：

以萘酰亚胺作为荧光团，通过哌嗪与N-2-氯乙酰氨基喹啉反应得到基于PET原理的荧光增强型Fe³⁺探针。实验结果表明，在pH=6.46 的0.01 mol/L Tris-HCl（乙腈：水=4：1，V/V）溶液中，探针能选择性识别溶液中的Fe³⁺，荧光最大增强10倍，不受其他离子的干扰;同时将探针硅烷化修饰后，共价键联到硅胶颗粒上得到荧光增强型Fe³⁺传感材料，可以检测水溶液中的Fe³⁺，在2.0×10^-5 ~1.4×10^-4 mol/L Fe³⁺离子含量范围内，荧光强度呈良好的线性关系（R²= 0.9023）。

关键词: 萘酰亚胺, 荧光, 探针, Fe³⁺, 传感材料

Abstract:

A naphthalimide-based turn-on fluorescent sensor for Fe³⁺ ion was designed and synthesized, whose receptor comprise piperazine and acetyl aminoquinoline. The results reveal that this novel probe exhibits a high selectivity to Fe³⁺ ion in neutral buffer aqueous. After silylation, the probe was covalently bonded to the silical particles to be a turn-on fluorescent sensing material, which showes a good linearity (correlation coefficient R₂=0.9023) in the range of 20-140 μmol/L of Fe³⁺ ion.

Key words: naphthalimide, fluorescence, probe, iron ions, sensing material

殷丽艳, 陈甜甜, 朱维平. 基于萘酰亚胺的Turn-on型Fe³⁺荧光探针[J]. 影像科学与光化学, 2014, 32(1): 84-90.

YIN Liyan, CHEN Tiantian, ZHU Weiping. A Turn-on Fluorescent Probe for Fe³⁺ Based on Naphthalimide[J]. Imaging Science and Photochemistry, 2014, 32(1): 84-90.

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基于萘酰亚胺的Turn-on型Fe³⁺荧光探针

A Turn-on Fluorescent Probe for Fe³⁺ Based on Naphthalimide

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