紫外光介导合成1,2,4-三芳基-1,4-丁二酮反应研究

doi:10.7517/j.issn.1674-0475.2015.04.265

影像科学与光化学 ›› 2015, Vol. 33 ›› Issue (4): 265-274.DOI: 10.7517/j.issn.1674-0475.2015.04.265

紫外光介导合成1,2,4-三芳基-1,4-丁二酮反应研究

黄宏丽¹, 高国林¹, 杨超¹, 夏吾炯¹, 陈晓明²

1. 哈尔滨工业大学基础与交叉科学研究院, 黑龙江哈尔滨 150080;
2. 温州医科大学检验医学院与生命科学学院, 浙江温州 325035

收稿日期:2015-03-31 修回日期:2015-04-22 出版日期:2015-07-16 发布日期:2015-07-16
通讯作者: 杨超, 陈晓明
基金资助:
中央高校基本科研业务费专项基金(HIT.NSRIF.2016046)和浙江省自然科学基金(LY12B02009)资助项目

Synthesis of 1,2,4-Triarylbutane-1,4-Diones Using UV Light Mediated

HUANG Hongli¹, GAO Guolin¹, YANG Chao¹, XIA Wujiong¹, CHEN Xiaoming²

1. Academy of Fundamental and Interdisciplinary Sciences, Harbin Institute of Technology, Harbin 150080, Heilongjiang, P. R. China;
2. School of Laboratory Medicine & Life Science, Wenzhou Medical University, Wenzhou 325035, Zhejiang, P. R. China

Received:2015-03-31 Revised:2015-04-22 Online:2015-07-16 Published:2015-07-16

摘要/Abstract

摘要：

在紫外光照射下,安息香发生裂解产生苯甲酰基自由基,与α,α-二芳基烯丙醇的双键发生自由基加成并伴随1,2-芳基迁移,实现了双键的双官能团化;同时该反应为有效合成1,2,4-三芳基-1,4-丁二酮化合物提供了一条新途径。该方法具有操作简单、反应条件温和等优点。

关键词: 紫外光, 1,2-芳基迁移, 双官能团化, 1,2,4-三芳基-1,4-丁二酮

Abstract:

Benzoyl radical could be generated from photochemical cleavage reaction of benzoin, which then might add to C=C double bond of α,α-diaryl allylic alcohols followed by 1,2-aryl migration to realize the difunctionalization of alkenes. The reaction provided an efficient approach to synthesize 1,2,4-triarylbutane-1,4-diones. The procedure is highlighted by its operational simplicity and mild reaction conditions.

Key words: UV light, 1,2-aryl migration, difunctionalization, 1,2,4-triarylbutane-1,4-dione

黄宏丽, 高国林, 杨超, 夏吾炯, 陈晓明. 紫外光介导合成1,2,4-三芳基-1,4-丁二酮反应研究[J]. 影像科学与光化学, 2015, 33(4): 265-274.

HUANG Hongli, GAO Guolin, YANG Chao, XIA Wujiong, CHEN Xiaoming. Synthesis of 1,2,4-Triarylbutane-1,4-Diones Using UV Light Mediated[J]. Imaging Science and Photochemistry, 2015, 33(4): 265-274.

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紫外光介导合成1,2,4-三芳基-1,4-丁二酮反应研究

Synthesis of 1,2,4-Triarylbutane-1,4-Diones Using UV Light Mediated

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