MSCT在胃癌分期诊断及化疗疗效预测中的应用

doi:10.7517/issn.1674-0475.211111

摘要/Abstract

摘要： 本研究旨在探讨在胃癌分期诊断及化疗疗效预测中应用多层螺旋CT (MSCT)的价值。选取100例胃癌患者进行本次研究,患者均接受新辅助化疗治疗,并行MSCT检查,根据化疗的疗效分组,有效组患者39例,无效组患者61例。研究结果显示:MSCT T分期与病理T分期Kappa值为0.706(P＜0.05),MSCT T分期诊断准确率为79.00%;MSCT N分期与病理N分期Kappa值为0.718(P＜0.05),MSCT N分期诊断准确率为83.00%;有效组CT肿瘤密度减低率、CT肿瘤体积减少率明显高于无效组(P＜0.05);CT肿瘤密度减低率、CT肿瘤体积减少率预测化疗有效的ROC曲线下面积分别0.922和0.811(P＜0.05)。胃癌分期应用MSCT有较好的诊断价值,且可预测化疗疗效。

关键词: 多层螺旋CT, 胃癌, 术前分期, 化疗疗效, 预测

Abstract: This study aimed to investigate the value of multi-slice spiral CT (MSCT) in staging diagnosis and chemotherapy efficacy prediction of gastric cancer. One hundred patients with gastric cancer treated were selected, all patients were treated with neoadjuvant chemotherapy and accepted MSCT examination. According to the efficacy of chemotherapy, 100 patients were divided into effective group with 39 cases and ineffective group with 61 patients. The results showed that, the Kappa value of MSCT T stage and pathological T stage was 0.706 (P<0.05), and the diagnostic accuracy rate of MSCT T stage was 79.00%. The Kappa value of MSCT N stage and pathological N stage was 0.718 (P<0.05), and the diagnostic accuracy rate of MSCT N stage was 83.00. The reduction rate of CT tumor density and CT tumor volume in the effective group were significantly higher than those in the ineffective group (P<0.05). In predicting the effectiveness of chemotherapy the area under ROC curve of CT tumor density reduction rate and CT tumor volume reduction rate were 0.922 and 0.811, respectively (P<0.05). MSCT has a good diagnostic value in preoperative staging of gastric cancer, and could predict the efficacy of chemotherapy.

Key words: multi-slice spiral CT, gastric cancer, preoperative staging, chemotherapy efficacy, prediction

秦佳敏, 刘广国, 王宏. MSCT在胃癌分期诊断及化疗疗效预测中的应用[J]. 影像科学与光化学, 2022, 40(3): 651-654.

QIN Jiamin, LIU Guangguo, WANG Hong. The Application of MSCT in Staging Diagnosis and Chemotherapy Efficacy Prediction of Gastric Cancer[J]. IMAGING SCIENCE AND PHOTOCHEMISTRY, 2022, 40(3): 651-654.

参考文献

[1] 孙启飞, 张敏, 诸晓艳. 螺旋CT在胃癌术前T分期中的价值[J]. 皖南医学院学报, 2018,37(1):60-63.
[2] 秦书敏, 刘亚良, 黄光建, 等. 3.0T MRI与MSCT对胃癌术前T分期的诊断价值[J]. 解放军医药杂志, 2018,30(12):29-22.
[3] Eisenhauer E A, Therasse P, Bogaerts J, et al. New response evaluation criteria in solid tumours:Revised RECIST guideline (version 1.1)[J]. European Journal of Cancer, 2009,45(2):228-247.
[4] Martínez-Salamanca J I, Huang W C, Millán I, et al. Prognostic impact of the 2009 UICC/AJCC TNM staging system for renal cell carcinoma with venous extension[J]. European Urology, 2011,59(1):120-127.
[5] 邵世虎, 曾小松, 夏宏林, 等. 多层螺旋CT在进展期胃癌术前TNM分期中的应用价值[J]. 安徽医药, 2018,22(5):921-923.
[6] 杨兴益, 李朝军, 郭浩. 腹部超声联合MSCT在胃癌术前TN分期中的诊断价值[J]. 解放军医药杂志, 2019,31(7):20-24.
[7] 邵华, 梁宏元. 多层螺旋CT三维重建对胃癌术前分期的价值[J]. 现代肿瘤医学, 2018,26(4):542-547.
[8] Spolverato G, Pawlik T M. Clinicopathological evaluation of recurrence in early gastric cancer[J]. American Journal of Surgery, 2019,157(3):202-207.
[9] 陈璐, 杨虹. 联合CT纹理分析和高分辨率CT图像特征预测肺腺癌组织学分化程度的研究[J]. 临床放射学杂志, 2021,40(4):707-711.
[10] 王鑫宏, 孙建忠, 胡婷婷, 等. 应用高分辨率CT局部放大重建提高肺部小结节结构精准诊断的价值[J]. 中华放射学杂志, 2020,54(2):119-123.
[11] 王智清, 陶芳旭, 张其林, 等. 多模态磁共振成像技术对胃癌术前T分期与术后病理诊断的对比研究[J]. 中国医学装备, 2018,15(11):69-73.
[12] 崔建新, 刘怡, 鲁意迅, 等. PET/MRI与增强CT对胃癌术前分期诊断价值的比较[J]. 解放军医学院学报, 2020,41(2): 147-150, 163.
[13] 张余黄, 张明英, 杨勇. MSCT胃癌征象及在术前TNM分期中的诊断价值分析[J]. 中国CT和MRI杂志, 2019,17(12):100-102, 106.
[14] 王群拴, 赵向乾. 64层多排螺旋CT三期增强扫描对术前胃癌淋巴结转移的诊断价值[J]. 解放军医药杂志, 2018,30(10):27-30.
[15] 贺文俊. MRI与MSCT对胃癌术前N分期及淋巴结转移的诊断价值分析[J]. 中国CT和MRI杂志, 2019,17(6):126-129, 153.