影像科学与光化学 ›› 2022, Vol. 40 ›› Issue (6): 1476-1480.DOI: 10.7517/issn.1674-0475.220818

• 综述与论文 • 上一篇    下一篇

床旁心脏超声联合Pcv-aCO2对于脓毒性休克容量反应性的预测价值

张怀伟1, 邵敏2, 单南冰1, 李彬彬1   

  1. 1. 阜阳市第五人民医院重症医学科, 安徽 阜阳 236000;
    2. 安徽医科大学第一附属医院重症医学科, 安徽 合肥 230000
  • 收稿日期:2022-08-10 出版日期:2022-11-23 发布日期:2022-11-15
  • 通讯作者: 李彬彬

Value of Bedside Echocardiography Combined with Pcv-aCO2 in Predicting Volume Reactivity of Septic Shock

ZHANG Huaiwei1, SHAO Min2, SHAN Nanbing1, LI Binbin1   

  1. 1. Intensive Care Unit, Fuyang Fifth People's Hospital, Fuyang 236000, Anhui, P. R. China;
    2. Intensive Care Unit, The First Affiliated Hospital of Anhui Medical University, Hefei 230000, Anhuii, P. R. China
  • Received:2022-08-10 Online:2022-11-23 Published:2022-11-15

摘要: 本文探讨床旁心脏超声联合中心静脉-动脉血二氧化碳分压差(Pcv-aCO2)对于脓毒性休克容量反应性的预测价值。选取110例脓毒性休克患者为研究对象,根据补液前后心脏指数变化值(ΔCI)分为容量有反应组(n=66)和无反应组(n=44)。容量有反应患者补液后Pcv-aCO2、呼吸变异指数(RVI)低于容量无反应患者(P<0.05),而下腔静脉直径(IVCD)高于容量无反应患者(P<0.05)。补液后Pcv-aCO2、RVI与ΔCI呈负相关(r=-0.432、-0.411,P<0.05)。Pcv-aCO2、RVI及二者联合预测容量反应性的ROC曲线下面积(AUC)分别为0.772、0.709和0.819(P<0.05)。床旁心脏超声联合Pcv-aCO2预测脓毒性休克容量反应性有较好的应用价值。

关键词: 床旁心脏超声, 中心静脉-动脉血二氧化碳分压差, 脓毒性休克, 容量反应性, 预测价值

Abstract: This study investigated the predictive value of bedside echocardiography combined with central venous arterial blood carbon dioxide differential pressure (Pcv-aCO2) in the volume response of septic shock. A total of 110 patients with septic shock were selected as the study subjects. According to the change of cardiac index (ΔCI) before and after fluid infusion, they were divided into volume response group (n=66) and non-response group (n=44). The Pcv-aCO2 and respiratory variation index (RVI) of volume responsive patients were significantly lower than those of volume unresponsive patients (P<0.05), while the diameter of inferior vena cava (IVCD) was significantly higher than that of volume unresponsive patients (P<0.05). After rehydration, Pcv-aCO2 and RVI were negatively correlated with ΔCI (r=-0.432、-0.411,P<0.05). The area under the ROC curve of Pcv-aCO2, RVI, and their combination for predicting volume reactivity was 0.772, 0.709, and 0.819, respectively (P<0.05). Bedside echocardiography combined with Pcv-aCO2 has good application value in predicting the volume reactivity of septic shock.

Key words: bedside ultrasound, central venous arterial blood carbon dioxide differential pressure, septic shock, volumetric reactivity, predictive value