Diagnostic Value of ECT Cerebral Perfusion Imaging, CT and MRI in Intractable Epilepsy

doi:10.7517/issn.1674-0475.190516

Abstract

Abstract: The clinical data of 53 patients with intractable epilepsy admitted to our hospital from October 2013 to December 2018 were retrospectively selected. All patients were examined by routine CT, MRI and SPECT during the interval of epilepsy. The accuracy of detection and localization of epileptic foci by three methods was observed. To explore the diagnostic value of single-photon emission computed tomography (PET-CT), CT and MRI in intractable epilepsy. Results:The rCBFdetected by SPECT of the affected side was lower than that of the healthy side[(46.05±7.62)vs(54.51±9.39), P < 0.05]. The NAA (cho+Cr) detected by MRI of the affected side was lower than that of the healthy side[(0.47±0.05) vs (0.69±0.11), P<0.05]. The detection rate and localization accuracy of SPECT for epileptogenic focus were 81.13% and 73.58%, respectively, which were higher than those of MRI and conventional CT (P<0.05). The detection rate and localization accuracy of combined SPECT, CT and MRI were 94.34% and 92.45%, higher than that of single diagnosis (P<0.05). The AUC of rCBF + NAA (cho + Cr) in predicting the location of epileptogenic focus was 0.923, the sensitivity and specificity were 82.26% and 98.91%, higher than that of rCBFand NAA (cho + Cr) (P<0.05). Conclusion:SPECT, and MRI have high clinical value in preoperative localization of intractable epilepsy. SPECT, has more advantage in the detection rate of epileptogenic foci and localization and lateral localization. Combined diagnosis is more helpful to improve the accuracy of localization.

Key words: intractable epilepsy, SPECT, CT, MRI, localization

LI Yuhua, LUO Xin, YU Kewen, GONG Xiao, LIU Wei, ZENG Xiangqin, HE Bing. Diagnostic Value of ECT Cerebral Perfusion Imaging, CT and MRI in Intractable Epilepsy[J]. Imaging Science and Photochemistry, 2019, 37(4): 378-384.

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