Clinical Diagnostic Value of Ultrasound Umbilical Artery S/D Combined with Serum IGF-1 and Bile Acid in Neonatal Asphyxia

doi:10.7517/issn.1674-0475.190715

Abstract

Abstract: By observing the difference of S/D ratio of umbilical artery blood flow, serum insulin-like growth factor (IGF-1) and bile acid (TBA) levels between neonates with asphyxia and normal neonates, the diagnostic value of S/D ratio of umbilical artery blood flow combined with serum IGF-1 and TBA in neonatal asphyxia was discussed. The results showed that the S/D ratio of pulse blood flow, serum IGF-1 and TBA were significantly different between neonatal asphyxia and normal 80 neonates, children with different degrees of asphyxia and neonatal ischemic-hypoxic encephalopathy (HIE). The results of multiple linear regression showed that umbilical artery blood flow S/D ratio, serum TBA, IGF-1 were closely related to the Apgar score of neonatal asphyxia evaluation index. The analysis of the receiver operating characteristic curve of the subjects showed that the S/D ratio of umbilical artery blood flow, serum IGF-1 and TBA had high application value in the diagnosis of neonatal asphyxia, and the combined detection of the above indicators had higher diagnostic value.

Key words: S/D, IGF-1, bile acid, neonatal asphyxia

DONG Ya'nan, PANG Yuan, LI Haipeng, SHU Zhan, XIAO Xiujuan. Clinical Diagnostic Value of Ultrasound Umbilical Artery S/D Combined with Serum IGF-1 and Bile Acid in Neonatal Asphyxia[J]. Imaging Science and Photochemistry, 2020, 38(1): 80-86.

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