Abstract: In ordr to discuss the ultrasonographic features of hyperplasia of mammary glands in different menstrual cycles, 102 patients with hyperplasia of mammary glands was analyzed in this study. From June 2017 to June 2019, they were selected as the subjects and examined by color Doppler ultrasound in different menstrual cycles (menstrual, proliferative and secretory stages). The sex hormones[estradiol (E2), progesterone (P)] were detected, and the ultrasonographic features of hyperplasia of mammary glands in different menstrual cycles were analyzed. The results showed that, among 102 cases of hyperplasia of mammary glands, 98 cases were diagnosed by color Doppler ultrasound, and the coincidence rate was 96.08%. Compared with pathological results, there was no significant difference (P>0.05). The thickness of breast body layer, duct width, breast pain rate and E2 level in proliferative period of patients with hyperplasia of mammary glands were significantly higher than those in menstrual period and secretory period. The level of P in proliferative period was significantly lower than that in secretory period, but significantly higher than that in menstrual period. The thickness of breast body layer, duct width, breast pain rate and E2 level in secretory period were higher than those in menstrual period, but there was no significant difference (P>0.05). This study confirms that, color Doppler ultrasonography has good diagnostic value for hyperplasia of mammary glands, and there are differences in ultrasonographic features of hyperplasia of mammary glands in different menstrual cycles. It can effectively evaluate the relationship between menstrual cycle, sex hormones and proliferative lesions.

Key words: menstrual cycles, hyperplasia of mammary glands, ultrasound, diagnosis