Application Value of Spiral CT Imaging Combined with Detection of Serum Copeptin and IL-18 Levels in Neurological Function and Prognosis Assessment of Patients with Acute Cerebral Infarction

doi:10.7517/issn.1674-0475.200615

Abstract

Abstract: A total of 74 patients with ACI in our hospital were selected as the research objects. According to the National Institutes of Health Stroke Scale (NIHSS) score, they were divided into severe group (NIHSS score >15 points, n=21), moderate group (NIHSS score 5-15 points, n=24), and mild group (NIHSS score <5 points, n=29). All received the detection of serum copeptin, IL-18 levels and spiral CT imaging. The results showed that with the aggravation of ACI neurological deficits, serum copeptin and interleukin 18 (IL-18) levels and peak time increased, while CBV and CBF decreased abnormally. The ROC curve showed that the area under the curve (AUC) of serum IL-18 combined with CBF to predict poor prognosis of ACI patients was the largest. It can be seen that there is a certain correlation between spiral CT imaging parameters, serum copeptin, IL-18 and the neurological function of ACI patients. The combination of the three provides the possibility to achieve individualized treatment of ACI patients and improve the prognosis.

Key words: spiral CT imaging, copeptin, interleukin 18, acute cerebral infarction, neural function, receiver operating characteristic curve

ZHANG Yanfeng, ZHANG Lan, HAN Hui. Application Value of Spiral CT Imaging Combined with Detection of Serum Copeptin and IL-18 Levels in Neurological Function and Prognosis Assessment of Patients with Acute Cerebral Infarction[J]. IMAGING SCIENCE AND PHOTOCHEMISTRY, 2021, 39(1): 34-39.

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