The Predictive Value of Cardiac Ultrasound and Diaphragmatic Activity Ultrasound Combined with Serum NT-proBNP in Patients with Invasive Mechanical Ventilation

doi:10.7517/issn.1674-0475.200617

Abstract

Abstract: The purpose of this article is to explore the value of echocardiography (TTE), phrenic activity (DE) ultrasound and serum N-terminal brain natriuretic peptide precursor (NT-proBNP) in predicting the outcome of patients with invasive mechanical ventilation after extubation. In this study, 85 patients undergoing invasive mechanical ventilation due to respiratory failure were selected as the research group. TTE ultrasound examination, DE ultrasound examination and SBT test were performed respectively to observe the outcome of patients after extubation. The results showed that among the 85 patients, 30.59% were unsuccessful and 69.41% were successful. After the SBT test, the E, E/e' and NT-proBNP values of the failed extubation group were higher than those of the successful extubation group (P<0.05), while DE value was lower than that of the successful extubation group (P<0.05). Binary logistic regression analysis showed that E/e', DE and Nt-proBNP were all influencing factors (P<0.05). In addition, the ROC curve showed that the the combined AUC of E/e', DE, NT-proBNP predicting the failure was 0.989, which was higher than any single test. It suggested that the predictive value of cardiac and DE ultrasound combined with serum NT-proBNP for successful extubation of patients with invasive mechanical ventilation was relatively high.

Key words: echocardiography, diaphragmatic activity, NT-proBNP, invasive mechanical ventilation, extubation

JIA Song, WEN Haiyan, WU Ping, LIU Donghui, HOU Liyan, ZHAO Ying. The Predictive Value of Cardiac Ultrasound and Diaphragmatic Activity Ultrasound Combined with Serum NT-proBNP in Patients with Invasive Mechanical Ventilation[J]. IMAGING SCIENCE AND PHOTOCHEMISTRY, 2021, 39(1): 61-66.

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