The Relationship between Nuclide Imaging and Immunoinflammatory Injury in Patients with Ventricular Reconstruction after Acute Myocardial Infarction

doi:10.7517/issn.1674-0475.210504

Abstract

Abstract: The purpose of this study was to investigate the role of radionuclide imaging in evaluating ventricular remodeling after acute myocardial infarction and its relationship with immune inflammatory injury. 90 patients with acute myocardial infarction were selected, including 43 patients with left ventricular remodeling and 47 patients without left ventricular remodeling. The left ventricular remodeling in patients with left ventricular end-diastolic volume index (LVEDVI), left ventricular end systolic volume index (LVESVI), summed thickening score (STS), total perfusion defect (TPD), survival myocardium, scar myocardium, endothelin-1 (ET-1), high sensitivity C-reactive protein (hs-CRP) and tumor necrosis factor α (TNF-α) were significantly higher than those without left ventricular remodeling (P<0.05). The level of serum nitric oxide (NO) and left ventricular ejection fraction (LVEF) in patients with left ventricular remodeling was significantly lower than that in patients without left ventricular remodeling (P<0.05). STS was positively correlated with ET-1 and hs-CRP (r=0.333 and 0.429, P<0.05); STS, ET-1 and hs-CRP were the influencing factors of ventricular remodeling after acute myocardial infarction (P<0.05). Radionuclide imaging has a certain value in the evaluation of ventricular remodeling after acute myocardial infarction, which is related to vascular endothelial injury and inflammatory factors.

Key words: radionuclide imaging technology, acute myocardial infarction, ventricular remodeling, vascular endothelial injury, inflammatory factors

YANG Lihui, DING Weiping. The Relationship between Nuclide Imaging and Immunoinflammatory Injury in Patients with Ventricular Reconstruction after Acute Myocardial Infarction[J]. IMAGING SCIENCE AND PHOTOCHEMISTRY, 2021, 39(6): 840-844.

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