Abstract: Analyzed the advantages of MRI-transrectal ultrasound targeted puncture combined with large prostate pathological slices for accurate diagnosis of prostate cancer. 125 patients with suspected prostate cancer were selected as research objects in the study. According to the puncture method they were divided into 60 cases in the control group and 65 cases in the study group. The control group underwent conventional systematic puncture guided by transrectal ultrasound, and the study group underwent magnetic resonance-transrectal ultrasound puncture combined with conventional system puncture, the patients in the research group underwent magnetic resonance-transrectal ultrasound targeted puncture, a total of 50 patients were diagnosed as prostate cancer, and underwent radical resection of prostate cancer. Then the pathological specimens of 25 patients were collected, and made into large slices, and the other 25 cases were made into regular slices. Compared with the control group, the total number of puncture needles and the number of positive needles for prostate cancer in the study group were lower (P<0.05), the number of patients with positive puncture was higher (P<0.05), the incidence of complications after puncture was lower (P<0.05). Compared with the conventional section group, the incidence of nerve involvement and capsule involvement in the pathological large section group was higher (P<0.05). In the comparison of pathological T staging between the two groups, the number of pT ≥ 3 cases detected in the large pathological section group was higher (P<0.05). Magnetic resonance-transrectal ultrasonography combined with prostate pathological large slices has a higher diagnostic value for prostate cancer.

Key words: magnetic resonance-transrectal ultrasound puncture, prostate pathology large section, prostate cancer, diagnostic advantages