Sensitivity and Accuracy Analysis of Energy Spectrum CT for the Diagnosis of Hepatocellular Carcinoma

doi:10.7517/issn.1674-0475.220720

Abstract

Abstract: This study investigated the value of spectral CT in the diagnosis of hepatocellular carcinoma. 110 cases of liver space occupying lesions were selected, all of them were given spectral CT and spiral CT examination. Among the 110 patients, 88 were diagnosed as hepatocellular carcinoma and 22 as focal nodular hyperplasia. The sensitivity, accuracy and negative predictive value of spectral CT in the diagnosis of hepatocellular carcinoma were significantly higher than those of spiral CT (P<0.05). In tumor diameter <3 cm, the detection rate of spectral CT was higher than that of spiral CT (P<0.05). The ratio of iodine uptake (IUR) in arterial phase, IUR in portal vein phase, standardized iodine concentration (NIC) in arterial phase, slope of energy spectrum curve (S) in arterial phase and S in portal vein phase of hepatocellular carcinoma were significantly lower than those in focal nodular hyperplasia (P<0.05). The area under the ROC curve (AUC) of arterial IUR, portal IUR, arterial NIC, arterial S and portal S in the diagnosis of hepatocellular carcinoma were 0.846, 0.767, 0.753, 0.811 and 0.715, respectively (P<0.05), the AUC of the combined diagnosis of the above parameters was 0.921, and the sensitivity and specificity were 90.00% and 88.00%, respectively. Energy spectrum CT has good application value in the diagnosis of hepatocellular carcinoma and is worthy of clinical use.

Key words: energy spectrum CT, spiral CT, hepatocellular carcinoma, diagnostic value

WANG Xueling, YUAN Qingling, YANG Juan. Sensitivity and Accuracy Analysis of Energy Spectrum CT for the Diagnosis of Hepatocellular Carcinoma[J]. IMAGING SCIENCE AND PHOTOCHEMISTRY, 2022, 40(6): 1339-1342.

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