Abstract: This article explored the prenatal ultrasound imaging features, the ratio of the width of the posterior horn of the lateral ventricle to the biparietal diameter, its value in determining the degree of fetal lateral ventriculomegaly (VM), and its relationship with early neonatal neurodevelopment. A total of 120 pregnant women with fetal VM were selected as the research objects,and they were divided into mild group (n=61), moderate group (n=37) and severe group (n=22) according to the degree of VM. All subjects underwent prenatal ultrasound to obtain fetal prenatal ultrasound imaging characteristics, the ratio of the width of the posterior horn of the lateral ventricle to the biparietal diameter. The results showed that the prenatal ultrasound imaging features of lateral VM fetuses were: as the degree of lateral VM increased, the ultrasound showed that the lateral ventricle widened gradually. The ratio of the width of the posterior horn of the lateral ventricle to the biparietal diameter of the fetal prenatal in the severe group was greater than that in the mild group and the moderate group, and the moderate group was greater than that in the mild group (P＜0.05). The ratio of posterior horn width to biparietal diameter of prenatal lateral ventricle was positively correlated with the degree of lateral VM (P＜0.05). The ratio of posterior horn width to biparietal diameter and width of lateral ventricle in neonates with early neurodevelopmental abnormality were higher than those in neonates with normal early neurodevelopment (P＜0.05). The ratio of posterior horn width and biparietal diameter of prenatal lateral ventricle, lateral ventricle width and early NBNA score were negatively correlated (P＜0.05). The area under the curve (AUC) of the ratio of prenatal posterior horn width to biparietal diameter combined with lateral ventricle width in predicting early neonatal neurodevelopmental abnormalities was 0.938. It indicated that the prenatal ultrasound imaging features of the fetus with lateral VM and the ratio of the width of the posterior horn of the lateral ventricle to the biparietal diameter could determine the degree of lateral VM, and the ratio of the width of the posterior horn of the lateral ventricle to the biparietal diameter was closely related to the early neonatal neurodevelopmental outcome.

Key words: fetus, lateral ventriculomegaly, prenatal ultrasound, ratio of posterior horn width to biparietal diameter, neurodevelopment