Imaging Science and Photochemistry ›› 2004, Vol. 22 ›› Issue (5): 363-369.DOI: 10.7517/j.issn.1674-0475.2004.05.363

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Synthesis and ESR Investigation of a New Hypocrellin Glycoside

XIA Sheng-qin, CHEN Jing-rong, WANG Xue-song, ZHANG Bao-wen   

  1. Technical Institute of Physics and Chemistry, Chinese Academy of Sciences, Beijing 100101, P. R. China
  • Received:2004-05-14 Revised:2004-06-09 Online:2004-09-23 Published:2004-09-23

Abstract: A new glycose derivatized hypocrellin B was synthesized in a facile way.The water-solubility and the absorbance in the phototherapeutic window was enhanced in the resulting product over hypocrellin B.Electron spin resonance (ESR) measurements indicated that this glycoside remained the photodynamic capability of generating 1O2,O2·-,·OH, and semiquinone anion radical.

Key words: hypocrellin B, glucosamine, water-solubility, reactive oxygen

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