Using Supramolecular Interaction to Improve the Water Solubility of Hypocrellin B:Synthesis of Adamantane-Modified HB and the Photodynamic Activity Study of Its Polymeric β-CD Inclusion System

doi:10.7517/j.issn.1674-0475.2007.05.380

Imaging Science and Photochemistry ›› 2007, Vol. 25 ›› Issue (5): 380-386.DOI: 10.7517/j.issn.1674-0475.2007.05.380

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Using Supramolecular Interaction to Improve the Water Solubility of Hypocrellin B:Synthesis of Adamantane-Modified HB and the Photodynamic Activity Study of Its Polymeric β-CD Inclusion System

QIAO Rui^1,2, ZENG Zhang-hua^1,2, LIU Yan-yan^1,2, CHEN Jing-rong¹, LI Cao¹, WANG Xue-song¹, ZHANG Bao-wen¹

1. Technical Institute of Physics and Chemistry, Chinese Academy of Sciences, Beijing 100080, P. R. China;
2. Graduate University of the Chinese Academy of Sciences, Beijing 100039, P. R. China

Received:2007-03-19 Revised:2007-04-06 Online:2007-09-23 Published:2007-09-23

Abstract

Abstract: An adamantane-modified hypocrellin B was designed and synthesized, and was dissolved in aqueous solutions by way of the supramolecular inclusion interaction between the adamantane group and β-cyclodextrin polymer. ESR technique was applied to study the photodynamic activities of the aqueous solution of the adamantane-modified hypocrellin B and β-cyclodextrin polymer.

Key words: hypocrellin B, adamantane, cyclodextrin polymer, inclusion interaction, photodynamic activity

CLC Number:

QIAO Rui, ZENG Zhang-hua, LIU Yan-yan, CHEN Jing-rong, LI Cao, WANG Xue-song, ZHANG Bao-wen. Using Supramolecular Interaction to Improve the Water Solubility of Hypocrellin B:Synthesis of Adamantane-Modified HB and the Photodynamic Activity Study of Its Polymeric β-CD Inclusion System[J]. Imaging Science and Photochemistry, 2007, 25(5): 380-386.

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Using Supramolecular Interaction to Improve the Water Solubility of Hypocrellin B:Synthesis of Adamantane-Modified HB and the Photodynamic Activity Study of Its Polymeric β-CD Inclusion System

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