Imaging Science and Photochemistry ›› 2020, Vol. 38 ›› Issue (2): 260-265.DOI: 10.7517/issn.1674-0475.190906

• Review and Articles • Previous Articles     Next Articles

Prognostic Value of SOFA Score Combined with Ultrasound in Sepsis Patients with AKI

ZHANG Zhen'en1, ZHENG Aidong1, YAN Xixiang1, SUN Xiaoyan2   

  1. 1. Department of Severe Medicine, Jianhu Hospital Affiliated to Nantong University, Yancheng 224700, Jiangsu, P. R. China;
    2. Department of Anesthesiology, Jianhu Hospital Affiliated to Nantong University, Yancheng 224700, Jiangsu, P. R. China
  • Received:2019-09-11 Online:2020-03-15 Published:2020-03-15
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Abstract: This article mainly explores the prognostic value of SOFA score combined with ultrasound in patients with sepsis and acute kidney injury (AKI). Fifty patients with sepsis and AKI in our hospital from January 2017 to January 2019 were selected as the observation group and divided into AKI stages 1, 2 and 3. The 50 patients with sepsis admitted in the same period were used as the control group. All patients were evaluated by SOFA score and ultrasound. The results showed that the PDU score of the observation group was lower than that of the control group (P<0.05); the RI value and SOFA score were higher than that of the control group (P<0.05). The PDU scores and SOFA scores were different among the three group at different stages. With the increase of AKI stage, the decrease of PDU score and the increase of SOFA score (P<0.05), but the RI value was not different between the three groups (P>0.05); the in-hospital mortality rate of 50 patients with sepsis and AKI was 44.00%. Univariate analysis found that age, mechanical ventilation time, ICU length of stay, AKI stage, septic shock, SOFA score, and PDU score were factors affecting the poor prognosis of patients (P<0.05); AKI stage 3, septic shock occurred, SOFA score, and PDU score were independent factors of poor prognosis in patients with sepsis and AKI (P<0.05). The larger the area under the ROC curve (AUC), the better the predictive power for prognosis. When AUC>70.00%, it has Clinical Value. The combination of the two is significantly higher than the SOFA score (AUC=74.28%) or PDU score (P<0.001). The above results show that patients with sepsis and AKI who use SOFA scores and ultrasound for assessing the prognosis of patients are better than using SOFA scores or ultrasound alone, and the combined predictive value is greater.

 

Key words: sepsis, acute kidney injury (AKI), sequential organ failure assessment(SOFA)score, ultrasound

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