Abstract: The aim of this paper is to analyse the diagnostic value of 64-slice spiral CT in the degree of coronary artery stenosis and plaque stability of Type 2 diabetes mellitus(T2DM) patients with coronary heart disease. 90 patients with coronary heart disease received in our hospital from February 2015 to February 2018 were selected and divided into two groups. One is the observation group (n=49), which with the combination of T2DM, the other is the control group (n=41), which without the combination of T2DM. Soft plaque and mixed plaque in the observation group were significantly more than those in the control group, and calcified plaque were significantly less than those in the control group. There was no significant difference in grade Ⅰ, Ⅱ and Ⅳ coronary artery stenosis between the two groups (P>0.05). Grade Ⅲ stenosis in the observation group was significantly higher than that in the control group (P<0.05). The sensitivity of 64-slice spiral CT in diagnosing ≥ 50% coronary artery stenosis was the lowest, but it gradually increased with the pathological deterioration. The positive predictive value increased with the pathological deterioration, but all of them were lower than the negative predictive value, indicating that there was an overestimation in the evaluation of coronary artery lesions with 64-slice spiral CT. For the patients with relatively serious coronary artery calcification, the diagnostic specificity decreases with the increase of calcification degrees, but high sensitivity and accuracy can still be maintained. In conclusion, multi-slice spiral CT has a high diagnostic value for the degree of coronary artery stenosis and plaque stability in patients with T2DM complicated with coronary heart disease, which can help to provide correct diagnosis and select appropriate treatment plan in clinical practice.

Key words: multi-slice spiral CT, type 2 diabetes, coronary heart disease, degree of coronary stenosis, plaque stability