The Clinical Application Value of MSCT Quantitative Parameters in Evaluating Fatty Liver Disease

doi:10.7517/issn.1674-0475.210205

Abstract

Abstract: This study was to investigate the practical value of quantitative parameters of multi-slice spiral CT (MSCT) in clinical evaluation of hepatic steatosis. 139 patients with fatty liver who were clearly diagnosed were selected as the fatty liver group, and 70 volunteers who underwent physical examination without liver disease during the same period were selected as the control group. Fatty liver group's liver fat percentage β value, total abdominal fat area (TFA), intra-abdominal fat area (VFA), subcutaneous fat area (SFA) measured values were higher than those of the control group (P<0.05). The liver CT values and liver bone mineral density (BMD) values of the fatty liver group were lower than those of the control group (P<0.05). The AUC values of liver CT value, liver BMD value, liver fat content percentage β value, TFA, VFA and SFA in diagnosing fatty liver were 0.609, 0.567, 0.896, 0.725, 0.848 and 0.674, respectively. MSCT quantitative parameters have high practical value in the clinical evaluation of liver fatty lesions, which can be comprehensively judged from several aspects such as the percentage of liver fat content β value and the area of fat in the abdominal cavity.

Key words: multi-slice spiral CT, fatty liver, receiver operator characteristic curve

WANG Jing, YANG Pengchun, YAN Caihua, DAI Chibing, QIN Tao. The Clinical Application Value of MSCT Quantitative Parameters in Evaluating Fatty Liver Disease[J]. IMAGING SCIENCE AND PHOTOCHEMISTRY, 2021, 39(5): 695-699.

References

[1] Gu J L, Liu S S, Du S X, et al. Diagnostic value of MRI-PDFF for hepatic steatosis in patients with non-alcoholic fatty liver disease:a meta-analysis[J]. European Radiology, 2019, 29(7):3564-3573.
[2] 么丽丽, 闫宇, 赵东杰, 等. 脂肪肝患者肝功能与肝纤维化血清学指标的相关分析[J]. 中国综合临床, 2018, 34(5):425-428.
[3] Speliotes E K. Thwart your destiny; effect of nonacoholic fatty liver disease genes on steatosis, liver injury and cirrhosis varies by body mass index[J]. Hepatology, 2018, 68(1):372-374.
[4] Jensen T, Niwa K, Hisatome I, et al. Increased serum uric acid over five years is a risk factor for developing fatty liver[J]. Scientific Reports, 2018, 8(1):e11735.
[5] 王永斌, 陆奎英, 苏勇, 等. 非酒精性脂肪肝患者肝功能, 氧化应激水平变化及临床意义[J]. 检验医学, 2020, 35(9):903-907.
[6] 林少波. 多层螺旋CT对不典型脂肪肝的诊断价值[J]. 深圳中西医结合杂志, 2016, 26(7):14-16.
[7] Liu Y, Radiology D O. Multislice spiral CT in the diagnosis of hepatic nodular disease in the background of fatty liver[J]. Journal of Imaging Research and Medical Applications, 2018, 2(6):61-62.
[8] 洪玉芹, 曾燕, 杨剑. 腹部脂肪CT定量评估与非酒精性脂肪肝严重程度的相关性[J]. 中国医学影像学杂志, 2020, 28(10):779-783.
[9] 中华医学会肝脏病学分会脂肪肝和酒精性肝病学组. 非酒精性脂肪性肝病诊断标准[J]. 中华肝脏病杂志, 2003, 11(2):71.
[10] 龚筑, 段庆红, 阮志兵, 等. 定量CT技术定量诊断脂肪肝的临床应用[J]. 实用放射学杂志, 2016, 32(6):950-954.
[11] 中国研究型医院学会肝病专业委员会, 中国医师协会脂肪性肝病专家委员会, 中华医学会肝病学分会脂肪肝与酒精性肝病学组, 等. 中国脂肪性肝病诊疗规范化的专家建议(2019年修订版)[J]. 中华肝脏病杂志, 2019, 27(10):748-753.
[12] 王凤永, 李滨, 张佳圆, 等. 多层螺旋CT增强扫描在脂肪肝背景下肝脏结节性疾病诊断中的价值[J]. 解放军预防医学杂志, 2019, 37(3):140-141.
[13] 解玉文. 分析64排螺旋CT在脂肪肝合并肝脏结节性疾病诊断中的应用效果[J]. 影像研究与医学应用, 2020, 4(23):166-168.
[14] 曲玉蕾, 王迎春, 万金鑫. 非酒精性脂肪性肝病与血清维生素D及骨密度的关系[J]. 临床肝胆病杂志, 2019, 35(9):2021-2025.
[15] 李畅, 王译妮, 彭云, 等. 多参数能谱CT成像对兔非酒精性脂肪性肝病定量诊断价值[J]. 实用放射学杂志, 2019, 35(6):992-996.
[16] 韦炜, 邓克学, 李君君. 定量诊断脂肪肝的影像学研究进展[J]. 中国科学技术大学学报, 2018, 48(10):862-867.
[17] 董志伟, 刘秋霞, 耿的玉, 等. 脂肪肝患者25-羟维生素D与骨密度和代谢综合征相关性研究[J]. 中国骨质疏松杂志, 2019, 25(12):1769-1772.
[18] 柳勇, 单奔, 周寒松, 等. 基于MR Dixon技术的肝脏脂肪半定量分析及其临床意义[J]. 实用放射学杂志, 2018, 34(2):291-295.