关键词: 超声造影, 膀胱占位性病变, T分期, 病理分级, 诊断价值

Abstract: This study explored the value of contrast-enhanced ultrasound (CEUS) in the differentiation of benign and malignant bladder occupying lesions. Eighty-two patients with space-occupying bladder lesions were selected as the research object, there were a total of 105 lesions. The differences of contrast-enhanced ultrasound parameters between benign and malignant lesions were compared, including time to arrival (AT), time to peak (TTP), peak intensity (PI) and washout time (WT). The results showed that 61 malignant lesions were confirmed pathologically after operation, and the sensitivity, specificity and accuracy of CEUS in diagnosing malignant bladder lesions were 90.16%, 90.91% and 90.48% respectively. PI and WT values of the high-grade malignant lesions were significantly higher than those of the low-grade malignant lesions (P<0.05). The PI and WT of T stage≥T3 lesions were significantly higher than those of Ta-1 and T2 lesions (P<0.05). The areas under the ROC curve of PI and WT for predicting high-grade lesions were 0.712 and 0.888, respectively. The areas under the ROC curve of PI and WT in predicting T stage ≥ T3 lesions were 0.812 and 0.852, respectively. CEUS is of high value in the diagnosis of bladder space occupying lesions, preoperative T staging and pathological grading, and is worthy of clinical use.

Key words: contrast-enhanced ultrasound, bladder occupying lesion, T stage, pathological grade, diagnostic value