影像科学与光化学 ›› 2022, Vol. 40 ›› Issue (2): 306-310.DOI: 10.7517/issn.1674-0475.210824

• 综述与论文 • 上一篇    下一篇

肺腺癌CT表现与病理分级的相关性研究

王锐1, 马彩玲1, 胡久丽2, 王琼鸽3, 胡潺潺3   

  1. 1. 承德医学院附属医院放射科, 河北 承德 067000;
    2. 承德医学院附属医院临床药学部, 河北 承德 067000;
    3. 承德医学院附属医院肿瘤科, 河北 承德 067000
  • 收稿日期:2021-08-30 出版日期:2022-03-15 发布日期:2022-03-08
  • 通讯作者: 胡潺潺
  • 基金资助:
    2021年承德市科学技术研究与发展计划项目(202109A076)

Correlation between CT Findings and Pathological Grade of Lung Adenocarcinoma

WANG Rui1, MA Cailing1, HU Jiuli2, WANG Qiongge3, HU Chanchan3   

  1. 1. Department of Radiology, Affiliated Hospital of Chengde Medical University, Chengde 067000, Hebei, P. R. China;
    2. Department of Clinical Pharmacy, Affiliated Hospital of Chengde Medical University, Chengde 067000, Hebei, P. R. China;
    3. Department of Oncology, Affiliated Hospital of Chengde Medical University, Chengde 067000, Hebei, P. R. China
  • Received:2021-08-30 Online:2022-03-15 Published:2022-03-08

摘要: 探讨肺腺癌CT影像学表现与组织病理学分级的相关性。回顾性分析149例经病理证实的肺腺癌患者资料。根据分级标准,将患者分为中高分化组(Ⅰ级与Ⅱ级)和低分化组(Ⅲ级),分析患者的肺腺癌CT影像表现与术后病理学分级的关系。结果显示:(1)中高分化组肿瘤最小径、最大径均显著低于低分化组(P<0.05);(2)中高分化组肿瘤边缘征象有47.4%出现分叶征,而低分化组有68.5%出现分叶征,二者间具有显著差异(P<0.01);(3)中高分化组26.3%伴有磨玻璃影,而低分化组3.7%伴有磨玻璃影,二者间具有显著差异(P<0.01)。总之,肺腺癌CT表现与其病理分级有显著相关性。

关键词: 肺腺癌, 计算机断层扫描, 病理分级, 相关性

Abstract: This article aims to explore the correlation between CT imaging findings and histopathological grading of lung adenocarcinoma.A retrospective collection of 149 patients with pathologically confirmed lung adenocarcinoma, according to the grading standard, the patients were divided into a moderately well-differentiated group (level Ⅰ and Ⅱ), a poorly differentiated group (level Ⅲ), and the relationship between CT imaging manifestations of lung adenocarcinoma and postoperative pathological grading was analyzed. Results: (1) The smallest and largest diameters of the tumors in the moderately well-differentiated group were significantly lower than those in the poorly differentiated group (P<0.05). (2) 47.4% of the tumor marginal signs in the moderately well-differentiated group showed lobular signs, while 68.5% in the poorly differentiated group, there was a significant difference between the two group (P<0.01). (3) 26.3% of the moderately differentiated group has ground glass shadow, and 3.7% of the poorly differentiated group, there was a significant difference between the two group (P<0.01). In short, the CT appearance of lung adenocarcinoma is significantly correlated with its pathological grade.

Key words: lung adenocarcinoma, computed tomography (CT), pathological grade, correlation