WBS联合SPECT/CT诊断肺癌四肢单发骨转移病变的价值

doi:10.7517/issn.1674-0475.210520

摘要/Abstract

摘要： 本研究探讨运用全身骨扫描（WBS）联合单光子发射计算机断层扫描系统（SPECT）/CT融合显像在肺癌四肢单发骨转移病变诊断中的价值。采用回顾性研究方法，选取肺癌患者140例，给予WBS、SPECT/CT融合显像。骨转移组中肺腺癌比例明显高于骨良性病变（P<0.05）；骨转移组骨质破坏、骨髓腔密度改变、骨皮质缺损比例明显高于骨良性病变（P<0.05）；WBS联合SPECT/CT融合显像诊断骨转移的灵敏性、特异性、准确性、阳性预测值和阴性预测值明显高于WBS检查（P<0.05）。WBS联合SPECT/CT融合显像诊断肺癌四肢单发骨转移病变有较好的价值。

关键词: 全身骨扫描, 单光子发射计算机断层扫描系统, 计算机断层扫描, 肺癌, 骨转移, 诊断价值

Abstract: The purpose of this study was to investigate the value of whole body bone scan (WBS) combined with single photon emission computed tomography (SPECT)/CT fusion in the diagnosis of single bone metastasis in lung cancer limbs. A retrospective study was conducted, 140 cases of lung cancer patients were selected and given WBS, SPECT/CT tomographic fusion examination. The proportion of adenocarcinoma in the bone metastasis group was significantly higher than that in benign bone lesions (P<0.05). The proportion of bone destruction, density change of bone marrow cavity and bone cortical defect in the bone metastasis group were significantly higher than that in benign bone lesions (P<0.05). The sensitivity, specificity, accuracy, positive predictive value and negative predictive value of WBS combined with SPECT/CT in diagnosis of bone metastasis were significantly higher than those of WBS (P<0.05). WBS combined with SPECT/CT fusion has a good value in the diagnosis of single bone metastasis in extremities of lung cance.

Key words: whole body bone scan, single photon emission computed tomography, computer tomo-graphy (CT), lung cancer, bone metastasis, diagnostic value

吴峰萍, 吴婧. WBS联合SPECT/CT诊断肺癌四肢单发骨转移病变的价值[J]. 影像科学与光化学, 2021, 39(6): 808-812.

WU Fengping, WU Jing. The Value of WBS Combined with SPECT/CT Tomographic Fusion in the Diagnosis of Solitary Bone Metastases in Extremities of Lung Cancer[J]. IMAGING SCIENCE AND PHOTOCHEMISTRY, 2021, 39(6): 808-812.

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