先天性感音神经性耳聋患儿的HRCT耳蜗定量参数与听觉传导通路DTI参数的相关性

doi:10.7517/issn.1674-0475.210101

摘要/Abstract

摘要： 本研究探讨分析先天性感音神经性耳聋（CSNHL）患儿高分辨率CT（HRCT）定量参数与听觉传导通路磁共振弥散张量成像（DTI）参数的关系。选取CSNHL患儿62例作为观察组，同时选取听力正常患儿50例作为对照组，分析各组HRCT、DTI参数差异。实验结果显示：观察组蜗神经管长度和宽度、耳蜗高度明显低于对照组（P<0.05）；观察组颞横回、颞上回、内囊后肢、听辐射和上橄榄核各向异性分数（FA）值明显低于对照组（P<0.05），表观弥散系数（ADC）值明显高于对照组（P<0.05）；观察组轻度患儿蜗神经管长度、蜗神经管宽度及耳蜗高度、听辐射FA值明显高于中重度、极重度患儿（P<0.05），ADC值明显低于中重度、极重度患儿（P<0.05）；蜗神经管长度、蜗神经管宽度及耳蜗高度与听辐射FA值呈正相关（P<0.05），与听辐射ADC值呈负相关（P<0.05）。研究证实：不同严重程度CSNHL患儿HRCT参数蜗神经管长度、蜗神经管宽度及耳蜗高度与听辐射FA、ADC有一定相关性。

关键词: 先天性感音神经性耳聋, 高分辨率CT, 磁共振弥散张量成像, 相关性

Abstract: The purpose of this study was to investigate the relationship between quantitative parameters of high resolution CT (HRCT) and diffusion tensor imaging (DTI) parameters of auditory pathway in children with congenital sensorineural hearing loss (CSNHL). A total of 62 children with CSNHL were selected as the observation group, and 50 cases of children with normal hearing were selected as the control group, the HRCT and DTI parameters of each group were analyzed. The experimental results showed that:The length and width of cochlear canal and cochlear height of the observation group were significantly lower than those of the control group (P<0.05). The fractional anisotropy (FA) values of transverse temporal gyrus, superior temporal gyrus, posterior limb of internal capsule, auditory radiation and superior olivary nucleus in the observation group were significantly lower than those in the control group (P<0.05), the apparent diffusion coeffecient (ADC) values were significantly higher than those in the control group (P<0.05). The length and width of cochlear canal and cochlear height of the mild children in the observation group were significantly higher than those of moderate severe and extremely severe children (P<0.05), FA value and ADC value of hearing radiation were significantly lower than that of moderate severe and extremely severe children (P<0.05). The length and width of cochlear canal and height of cochlear were positively correlated with auditory radiation FA (P<0.05), and negatively correlated with ADC of auditory radiation (P<0.05). This study confirmed that some HRCT and DTI parameters of CSNHL with different severity are different, the length and width of the cochlear canal and the height of the cochlea are correlated with FA and ADC of auditory radiation.

Key words: congenital sensorineural hearing loss, high resolution CT, magnetic resonance diffusion tensor imaging, correlation

杜玲, 刁锋, 计明. 先天性感音神经性耳聋患儿的HRCT耳蜗定量参数与听觉传导通路DTI参数的相关性[J]. 影像科学与光化学, 2021, 39(5): 653-657.

DU Ling, DIAO Feng, JI Ming. Correlation between Quantitative Cochlear Parameters of HRCT and DTI Parameters of Auditory Pathway in Children with Congenital Sensorineural Hearing Loss[J]. IMAGING SCIENCE AND PHOTOCHEMISTRY, 2021, 39(5): 653-657.

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