影像科学与光化学 ›› 2023, Vol. 41 ›› Issue (1): 164-168.DOI: 10.7517/issn.1674-0475.221031

• 综述与论文 • 上一篇    下一篇

术前门静脉CTA预测肝硬化食管胃静脉曲张破裂出血的研究

赵永昌1, 徐菁2, 陈士新1, 马永刚1   

  1. 1. 西安交通大学医学院附属三二〇一医院影像科, 陕西 汉中 723000;
    2. 西安交通大学医学院附属三二〇一医院消化内科, 陕西 汉中 723000
  • 收稿日期:2022-10-21 出版日期:2023-01-23 发布日期:2023-01-31
  • 通讯作者: 赵永昌

Research on Prediction of Esophagogastric Variceal Bleeding in Cirrhotic Patients by Preoperative Portal Vein CTA

ZHAO Yongchang1, XU Jing2, CHEN Shixin1, MA Yonggang1   

  1. 1. Department of Imaging, 3201 Hospital Affiliated to Medical College of Xi'an Jiaotong University, Hanzhong 723000, Shaanxi, P. R. China;
    2. Department of Gastroenterology, 3201 Hospital Affiliated to Medical College of Xi'an Jiaotong University, Hanzhong 723000, Shaanxi, P. R. China
  • Received:2022-10-21 Online:2023-01-23 Published:2023-01-31

摘要: 本研究探讨术前门静脉CT血管造影(CTA)预测肝硬化食管胃静脉曲张破裂出血的价值。选取90例肝硬化食管胃静脉曲张破裂出血患者作为出血组、选取肝硬化食管胃静脉曲张但是未发生破裂出血的90例患者作为对照组,对比两组患者手术前的CTA检查结果,包括门静脉主干(MPV)直径、脾静脉(SPV)直径、胃左静脉(LGV)直径。比较两组患者的血清总胆红素(TBIL)、血清碱性磷酸酶(ALP)、凝血酶原活动度(PTA)浓度。分析具有统计学意义的指标在预测患者发生胃静脉曲张破裂出血方面的价值。出血组患者的MPV直径、SPV直径、LGV直径测定值均显著大于对照组(P<0.05)。MPV直径、SPV直径、LGV直径预测患者发生出血的AUC值分别为0.800、0.660、0.743。出血组和对照组的TBIL、ALP比较,差异均不具有统计学意义(P>0.05);出血组的PTA大于对照组,且差异具有统计学意义(P<0.05)。Logistic回归模型分析结果显示:MPV直径、SPV直径、LGV直径、PTA增大是患者发生食管胃静脉曲张破裂出血的危险因素(P<0.05)。术前CTA检查MPV、SPV、LGV的直径预测肝硬化食管胃静脉曲张破裂出血具有较高价值,三项参数与患者发生食管胃静脉曲张破裂出血的关系密切。

关键词: 门静脉, CT血管造影, 肝硬化, 食管胃静脉曲张, 出血

Abstract: This study evaluated the value of preoperative portal vein CT angiography (CTA) in predicting esophagogastric variceal bleeding in patients with liver cirrhosis. 90 patients with cirrhotic esophagogastric varices bleeding were selected as bleeding group, and 90 cirrhotic patients with esophagogastric varices without bleeding were selected as control group. Compared the preoperative CTA test results of the two groups, which including the diameter of main portal vein (MPV), splenic vein (SPV) and left gastric vein (LGV). The concentrations of serum total bilirubin (TBIL), serum alkaline phosphatase (ALP) and prothrombin activity (PTA) were compared between the two groups. Analyzed the statistically significant indexes which was valuable in predicting gastric variceal bleeding. The measured values of MPV diameter, SPV diameter and LGV diameter in the bleeding group were significantly higher than those in the control group(P<0.05). The AUC values of MPV diameter, SPV diameter and LGV diameter for predicting bleeding were 0.800, 0.660 and 0.743, respectively. There was no significant difference in TBIL and ALP between bleeding group and control group (P>0.05). The PTA in bleeding group was higher than that in control group, and the difference was statistically significant (P<0.05). Logistic regression model analysis showed that the increase of MPV diameter, SPV diameter, LGV diameter and PTA were the risks of esophagogastric variceal bleeding (P<0.05). Preoperative CTA examination of the diameters of MPV, SPV and LGV is of high value in predicting esophagogastric variceal bleeding in patients with liver cirrhosis, and the three parameters are closely related to esophagogastric variceal bleeding.

Key words: portal vein, CT angiography, liver cirrhosis, esophagogastric varices, hemorrhage