影像科学与光化学 ›› 2022, Vol. 40 ›› Issue (3): 535-539.DOI: 10.7517/issn.1674-0475.211226

• 综述与论文 • 上一篇    下一篇

彩超引导下纳米炭示踪在PTC患者微创手术中的应用

曹一鸣, 卿佳林, 王丹英, 张敏敏   

  1. 广西柳州市人民医院乳腺甲状腺外科, 广西 柳州 545006
  • 收稿日期:2021-12-20 出版日期:2022-05-15 发布日期:2022-05-27
  • 通讯作者: 广西卫生和计划生育委员会自筹经费科研课题(Z20170650)

The Application of Color Ultrasound-guided Nano-carbon Tracing in Minimally Invasive Surgery of PTC Patients

CAO Yiming, QING Jialin, WANG Danying, ZHANG Minmin   

  1. Department of Breast and Thyroid Surgery, Liuzhou People's Hospital, Liuzhou 545006, Guangxi, P. R. China
  • Received:2021-12-20 Online:2022-05-15 Published:2022-05-27

摘要: 本文探讨术前应用彩超引导下注射纳米炭混悬液指导甲状腺乳头状癌(PTC)患者实施腔镜下手术的价值。选取98例PTC患者作为研究对象,根据患者是否采用超声引导下纳米炭示踪技术,将患者分为示踪组(58例)和传统组(40例)。示踪组患者术前采用彩超引导下注射纳米炭混悬液,指导手术医生实施颈中央区淋巴结清扫,传统组则采用传统手术方法实施颈中央区淋巴结清扫,采用生化分析检测血钙水平,酶联免疫吸附法检测血清PTH水平。示踪组的手术时间、术中出血量均显著低于传统组(P<0.05);示踪组中央区淋巴结清扫数目、中央区淋巴结阳性数目均高于传统组(P<0.05);两组患者术后24 h、72 h两组患者的血清PTH、血钙水平均较本组患者手术前均降低(P<0.05),传统组患者的血清PTH、血钙水平较示踪组降低更为显著(P<0.05);示踪组的术后并发症率低于传统组(P<0.05)。彩超引导下注射纳米炭混悬液淋巴结示踪指导PTC患者的腔镜下中央区淋巴结清扫术有较高的实用价值,有利于缩短手术时间,降低手术难度,提高淋巴结清扫效率,降低甲状旁腺副损伤及手术并发症的发生率。

关键词: 彩超, 纳米炭, 甲状腺乳头状癌, 甲状腺全切, 中央区淋巴结清扫

Abstract: This article discussed the value of preoperative color Doppler ultrasound-guided injection of nano-carbon suspension to guide laparoscopic surgery in patients with papillary thyroid carcinoma (PTC). Ninety-eight patients with PTC were selected as the research objects, according whether the patients adopted the nano-carbon tracking technology with ultrasound-guided, the patients were divided into the tracer group with 58 cases and the traditional group with 40 cases. The patients in the tracer group were injected with nano-carbon suspension under the guidance of color Doppler ultrasound before operation, and the surgeons were instructed to perform lymph node dissection in the central area of the neck. The traditional group were performed lymph node dissection in the central area of the neck by traditional surgical methods. The calcium levels in blood were analyzed by biochemical assays and the serum PTH level was detected by linked immunosorbent assay. The operation time and intraoperative blood loss in the tracer group were significantly lower than those in the traditional group (P<0.05). The number of dissected central lymph nodes and the number of positive central lymph nodes in the tracer group were higher than those in the traditional group (P<0.05). At 24 hour and 72 hour after the operation, the serum PTH and blood calcium levels in the two groups were lower than 535those in the same group before the operation (P<0.05). Compared with the tracer group, the serum PTH and blood calcium levels in the traditional group were significantly lower (P<0.05). The postoperative complication rate in the tracer group was lower than that in the traditional group (P<0.05). Color Doppler-guided injection of nano-carbon suspension lymph node tracing to guide endoscopic central lymph node dissection in patients with PTC has higher practical value, which is benefit to shorten the operation time, reduce the difficulty of operation, improve the efficiency of lymph node dissection, and reduce parathyroid glands incidence of collateral injuries and surgical complications.

Key words: color Doppler ultrasound, nano carbon, papillary thyroid carcinoma, total thyroidectomy, central lymph node dissection