影像科学与光化学 ›› 2006, Vol. 24 ›› Issue (5): 382-390.DOI: 10.7517/j.issn.1674-0475.2006.05.382

• 应用与发展 • 上一篇    下一篇

用于生物标记的半导体量子点研究

余启钰1,2, 刘春艳1   

  1. 1. 中国科学院, 理化技术研究所, 北京, 100080;
    2. 中国科学院研究生院, 北京, 100039
  • 收稿日期:2006-05-16 修回日期:2006-06-14 出版日期:2006-09-23 发布日期:2006-09-23
  • 通讯作者: 刘春艳,E-mail:cyliu@mail.ipc.ac.cn.
  • 基金资助:
    国家自然科学基金项目(90306003,90406024)

Research on Semiconductor Quantum Dots for Biological Imaging

YU Qi-yu1,2, LIU Chun-yan1   

  1. 1. Technical Institute of Physics and Chemistry, Chinese Academy of Sciences, Beijing 100080, P. R. China;
    2. Graduate School of the Chinese Academy of Sciences, Beijing 100039, P. R. China
  • Received:2006-05-16 Revised:2006-06-14 Online:2006-09-23 Published:2006-09-23

摘要: 半导体量子点的独特光学性质使之成为理想的荧光探针材料,在生物医学领域具有广阔的应用前景.本文评述了目前量子点合成、表面修饰、结合生物分子的方法,以及半导体量子点在生物标记应用中相对于传统有机染料的优点.

关键词: 半导体量子点, 荧光探针, 生物标记

Abstract: The unique optical properties of semiconductor quantum dots(QDs) make them very promising as fluorescent probes in biomedical application.We review current approaches to the synthesis,surface modification and bioconjugation of QDs,as well as their advantages over traditional organic dyes in biological imaging.

Key words: semiconductor quantum dots, fluorescent probes, biological imaging

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