Abstract: The purpose of this study is to analyze the relationship between the imaging characteristics of TE(transient elastography) in patients with NAFLD(non-alcoholic fatty liver disease) and their severity and insulin resistance. We chose 112 patients with NAFLD and 108 patients with health check-up, compared the baseline data of the two groups of patients, and grouped the patients with NAFLD according to the condition and compared the relevant data.Research shows that the liver function, serum insulin, HOMA-IR(insulin resistance index) were significantly higher in the NAFLD group than in the control group (P< 0.05). With the increase of fatty liver severity, the general age of patients increased, more men than women, liver hardness, liver function, and insulin-related indicators all increased significantly, with significant differences (P<0.05). The ROC curve analysis showed that CAP(controlled attenuation parameter) had high diagnostic value for mild, moderate and severe NAFLD, with sensitivity of 0.865, 0.861, 0.931, and specificity of 0.614, 0.819, and 0.822, respectively. With the aggravation of severity's condition in NAFLD, the CAP and HOMA-IR values increased significantly and were positively correlated(r=0.536, r=0.479).The TE imaging of NAFLD patients is closely related to the severity of NAFLD. Insulin resistance can also be clinically assisted in the diagnosis of NAFLD.

Key words: non-alcoholic fatty liver disease(NAFLD), transient elastography(TE), insulin resistance(IR)