The Value of CDFI in Identifying Benign and Malignant Tumors of Male Breast and Its Correlation with CXCL1, Gab2 and MVD

doi:10.7517/issn.1674-0475.200601

Abstract

Abstract: In this article, 18 male patients with malignant breast tumors were selected as the research group, while 41 male with benign breast tumors and 50 healthy males in the same period were included as benign control group and healthy control group. Through comparative analysis, it was found that the CDFI parameters[pulse index (PI), resistance index (RI), blood flow velocity (PSV)] of the research group were higher than those of the benign control group and the healthy control group (P<0.05). The combined AUC value of PI, RI and PSV in the diagnosis of male breast malignant tumors was as high as 0.854, which was of a high application value. In the research group, there was a positive correlation between PI, RI, PSV and the level of CXC type chemokine ligand 1 (CXCL1), as well as the level of GRB related protein 2 (Gab2) and microvessel density (MVD) (P<0.05). Our research showed that CDFI had a high application value in identifying benign and malignant breast tumors in men, and it is positively correlated with the expression of CXCL1, Gab2 and MVD in patients.

Key words: breast cancer, male, color doppler flow imaging, CXC-type chemokine ligand 1, GRB-related protein 2, microvessel density

WU Xiaosheng, LIU Yang, WU Baohui. The Value of CDFI in Identifying Benign and Malignant Tumors of Male Breast and Its Correlation with CXCL1, Gab2 and MVD[J]. IMAGING SCIENCE AND PHOTOCHEMISTRY, 2021, 39(1): 139-144.

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