Abstract: This study explored the clinical application value of color Doppler flow imaging (CDFI) in the diagnosis of biliary atresia (BA). Sixty-eight infants with persistent jaundice and biliary atresia were selected as BA group, and 64 healthy newborns during the same period were selected as the control group. CDFI examination was performed on both groups to analyze the changes in ultrasonic characteristics. The results showed that the abnormality rate of gallbladder morphology in the BA group was 89.71%, the ultrasound display rate of the left and right hepatic ducts in the BA group was 100.00%, and the extrahepatic bile duct ultrasound display rate in the BA group was 100.00%, which were all higher than that of the control group (P<0.05). The AUC values of mean portal velocity (Vpv), anteroposterior diameter of portal vein (Dha), portal vein resistance index (RIha) and splenic vein resistance index (RIspa) were 0.899, 0.774, 0.731 and 0.648, respectively. CDFI has high clinical practical value as a non-invasive method for diagnosing children with BA, and it is of high value to make comprehensive judgments based on the gallbladder morphology and blood flow parameters.

Key words: color Doppler flow imaging, biliary atresia, gallbladder morphology, jaundice