The Relationship between Sinus CT Score, EOS Count and CRSwNP Patients Complicated with AAHR

doi:10.7517/issn.1674-0475.211142

Abstract

Abstract: This study investigated the value of sinus CT score and eosinophil (EOS) count in the diagnosis of chronic rhinosinusitis with nasal polyps (CRSwNP) complicated with asymptomatic airway hyperresponsiveness (AAHR). A clinical study was conducted on 127 confirmed CRSwNP patients, according to whether the patients were accompanied by AAHR, they were divided into observation group (71 cases) and CRSwNP patients without airway hyperresponsiveness (56 cases) as control group. Performed the sinus CT three-dimensional reconstruction and scoring, and detected the levels of EOS in nasal polyps and peripheral blood of the two groups. The expression levels of EOS in nasal polyps and peripheral blood tissues of the observation group were higher than those of the control group (P<0.05). The AUC value of EOS in nasal polyps to diagnose CRSwNP patients complicated with AAHR was 0.852, and in peripheral was 0.821. The CT scores of olfactory cleft and ethmoid sinus in the observation group were significantly higher than those in the control group (P<0.05). There was no significant difference in maxillary sinus CT scores between the observation group and the control group (P>0.05). The AUC value of olfactory fissure CT score in the diagnosis of CRSwNP patients complicated with AAHR was 0.761, and of ethmoid sinus was 0.864. CRSwNP patients complicated with AAHR are serious. The detection of EOS expression and sinus CT scores have a certain value in judging whether CRSwNP patients complicated with AAHR.

Key words: CT three-dimensional reconstruction, eosinophils, chronic sinusitis, nasal polyps, asymptomatic airway hyperresponsiveness, diagnosis

XIE Huanqing, XU Guozhen. The Relationship between Sinus CT Score, EOS Count and CRSwNP Patients Complicated with AAHR[J]. IMAGING SCIENCE AND PHOTOCHEMISTRY, 2022, 40(3): 453-458.

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