Predictive Analysis of CTP Parameters on the Prognosis of Patients with Middle Cerebral Artery Stenosis

doi:10.7517/issn.1674-0475.220112

Abstract

Abstract: This study explored the application value of CT perfusion (CTP) parameters in evaluating the prognosis and cognitive function of patients with middle cerebral artery stenosis. Selected 109 patients with middle cerebral artery stenosis and analyzed the ratio of affected side to healthy side of cerebral blood volume (CBV), time to peak (TTP), mean transit time (MTT) and delay time (Delay) in patients with different prognosis and cognitive function, as well as the value of CBV, TTP, MTT and Delay patient health ratio in predicting prognosis and cognitive impairment. The ratio of affected side to healthy side of CBV in patients with middle cerebral artery severe stenosis and poor prognosis was significantly lower than that in patients with moderate stenosis and good prognosis (P<0.05). The ratio of affected side to healthy side of MTT and Delay were significantly higher than those with moderate stenosis and good prognosis (P<0.05). The ratio of affected side to healthy side of CBV in patients with middle cerebral artery stenosis and cognitive impairment was significantly lower than that in patients without cognitive impairment (P<0.05). The areas under the ROC curve of ratio of affected side to healthy side of CBV, MTT and Delay in predicting middle cerebral artery stenosis poor prognosis were 0.852, 0.677 and 0.895, respectively (P<0.05). The area under the ROC curve of ratio of affected side to healthy side of CBV in predicting middle cerebral artery stenosis with cognitive impairment was 0.700 (P<0.05). The ratio of affected side to healthy side of CBV, MTT and Delay patient health ratio have certain application value in predicting the prognosis and cognitive function of patients with middle cerebral artery stenosis.

Key words: CT perfusion, middle cerebral artery stenosis, prognosis, cognitive function

WANG Jianbing, HUANG Shuchun, ZHAO Yanwen, WANG Bibai, LU Wei, HU Dingju, LIU Yinyin. Predictive Analysis of CTP Parameters on the Prognosis of Patients with Middle Cerebral Artery Stenosis[J]. IMAGING SCIENCE AND PHOTOCHEMISTRY, 2022, 40(4): 843-847.

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