The Effect of Intravascular Drug Balloon in the Treatment of Lower Extremity ASO and Its Influence on the Ultrasound Parameters of the Affected Extremity

doi:10.7517/issn.1674-0475.220609

Abstract

Abstract: The aim of the study was to investigate the therapeutic effect of lower extremity arteriosclerotic occlusive disease (ASO) and its effect on the ultrasonographic parameters of the affected limb. A total of 120 lower limb ASO patients were divided into an observation group (n=58) and a control group (n=62). The observation group was treated with intracavitary drug balloon and the control group was treated with ordinary balloon, the levels of serum C-reactive protein (CRP), interleukin-16 (IL-16) and SF-36 and so on were observed. At 24 hours after operation, CRP, High sensitivity C-reactive protein (hs-CRP), IL-6 and endothelin-1 (ET-1) in the observation group were significantly lower than those in the control group (P<0.05), while nitric oxide (NO) was significantly higher than those in the control group (P<0.05). The scores of ankle brachial index (ABI), ultrasonic parameters of affected limband SF-36 in the observation group were significantly higher than those in the control group 12 months after operation (P<0.05). The restenosis rate and late lumen loss (LLL) of target vessels in the observation group were significantly lower than those in the control group (P<0.05). Endovascular drug balloon has a good effect in the treatment of lower extremity ASO, improves affected limb function and the quality of life, reduces the inflammatory reaction of patients.

Key words: arteriosclerotic occlusive disease of lower limbs, drug balloon, therapeutic effect, inflammatory factor

YANG Yanlin, WU Guoliang, TIAN Shaoyong, WANG Chunyan, ZHAO Pengfei. The Effect of Intravascular Drug Balloon in the Treatment of Lower Extremity ASO and Its Influence on the Ultrasound Parameters of the Affected Extremity[J]. IMAGING SCIENCE AND PHOTOCHEMISTRY, 2022, 40(6): 1491-1496.

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