Abstract: This study investigated the value of magnetic resonance imaging (MRI) and thrombela-stogram (TEG) parameters in the diagnosis of hemorrhagic transformation (HT) after thrombolysis in acute cerebral infarction (ACI). 62 ACI patients with HT who received thrombolytic therapy were selected as HT group, and 80 ACI patients without HT transformation who received thrombolytic therapy at the same time were selected as control group. The MRI parameters and TEG parameters of the two groups were compared, and the final clinical diagnosis results were used as the judgment basis to calculate the value of MRI parameters and TEG in diagnosing HT in ACI patients after thrombolysis. The results showed that the phase signal characteristics of susceptibility weighted imaging (SWI) in HT group were mainly characterized by high signal, the proportion of patients with high signal in HT group was significantly higher than that in control group (P<0.05), and the proportion of patients with low signal and mixed signal in HT group was lower than that in control group (P<0.05). The sensitivity of SWI, diffusion weighted imaging (DWI) and T1-weighted imaging (T1WI) in the diagnosis of HT were 88.71%, 62.90% and 69.35%, respectively, and the specificity were 86.25%, 80.00% and 82.50%, respectively. The coagulation composite index (CI) value of HT group was significantly lower than that of control group (P<0.05). The AUC values of SWI, DWI and T1WI in diagnosing HT in patients with ACI thrombolysis were 0.875, 0.715 and 0.759, respectively. The AUC value of CI value in TEG parameters for diagnosing HT in patients with ACI thrombolysis was 0.720. MRI and TEG parameters have high value in the diagnosis of HT in patients with ACI thrombolysis.

Key words: magnetic resonance imaging, thromboela-stogram, diagnosis, acute cerebral infarction, hemorrhagic transformation